Dron Kumar¹, Rahul Kumar Tondey¹, Narendra Kumar Jurri¹, Kamlesh Kumar¹, Chetan Kumar¹, Bhisesar Sahu¹ and Gyanesh Kumar Sahu²

¹Rungta Institute of Pharmaceutical Sciences Kohka, Bhilai, India
²Rungta Institute of Pharmaceutical Sciences and Research Kohka, Bhilai, India

*Corresponding Author: Gyanesh Kumar Sahu, Professor and Dean, Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India

Received: February 04, 2025; Published: February 15, 2025

Abstract

The dermatological disease known as hyperpigmentation of the skin causes the skin to become darker or discolored. Treatments for hyperpigmentation problems frequently have low patient compliance and take a very long time to show benefits. Oral formulations of therapeutic agents including tranexamic acid, melatonin, and cysteamine hydrochloride are administered after topical formulations of traditional agents like hydroquinone, kojic acid, and glycolic acid as the first line of treatment for hyperpigmentation. Chemical peels and laser therapy are second-line methods that are administered under the supervision of qualified specialists. Nevertheless, these treatments have drawbacks and side effects such erythema, skin peeling, and dryness, and they take a long time to start showing results. These drawbacks of the traditional therapies opened the door for more investigation into more recent approaches to hyperpigmentation management. Novel formulations include phytochemicals, liposomes, platelet-rich plasma, solid lipid nanocarriers, and microneedling are a few of these treatments. Several hyperpigmentation problems and their processes, as well as new and developing therapeutic approaches for managing hyperpigmentation, are the main topics of this review.

Keywords: Pigmentation; Medication; Microneedling

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Citation

Citation: Gyanesh Kumar Sahu., et al. “Recent Advances in the Formulation of Topical Creams for Hyperpigmentation Treatment". Acta Scientific Pharmaceutical Sciences 9.3 (2025): 22-28.

Copyright

Copyright: © 2025 Gyanesh Kumar Sahu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.