A Comprehensive Review of Polycystic Ovarian Disease (PCOD): Pathophysiology, Diagnosis, and Herbal Therapeutic Approaches

Sangeeta Manjhi¹, Tanu Engle¹, Pratibha Kanwar¹, Kamini Sonwani², Anjali¹, Harish Sharma³ and Gyanesh Kumar Sahu¹*

¹Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India
²Rungta Institute of Pharmaceutical Sciences, Kohka, Kurud, Bhilai, India
³School of Pharmacy, Anjaneya University, Raipur, India

*Corresponding Author: Dr. Gyanesh Kumar Sahu, Professor and Dean, Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India.

Received: November 29, 2024; Published: December 20, 2024

Abstract

The rising prevalence of diabetes mellitus has spurred significant interest in alternative therapies, particularly those derived from herbal sources. Terminalia arjuna (commonly known as Arjuna) is a well-known medicinal plant traditionally used in Ayurveda for its cardio protective, antioxidant, and hypoglycemic properties. This review explores the potential of formulating Gutika (an Ayurvedic herbal tablet) using Arjuna extract as a novel approach for managing antidiabetic activity.

The bioactive compounds in Arjuna, such as flavonoids, glycosides, and tannins, have demonstrated significant hypoglycemic and insulin-sensitizing effects in various studies. This review highlights the formulation techniques, pharmacological properties, and pre mechanisms of action of Arjuna extract in improving glucose metabolism are discussed.

clinical and clinical evidence supporting its role in glycemic control. Additionally, the safety profile, dose optimization, and potential

The findings suggest that Gutika prepared from Arjuna extract offers a promising herbal alternative for managing diabetes, poten tially reducing dependency on synthetic drugs and their associated side effects. Future research should focus on clinical trials and formulation standardization to establish its efficacy and safety for widespread use

Keywords: Terminalia arjuna; Cardio Protective; Compounds

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Citation

Citation: Gyanesh Kumar Sahu., et al. “Traditional and Modern Approaches to Diabetes: A Review on Terminalia arjuna Gutika". Acta Scientific Pharmaceutical Sciences 9.1 (2025): 87-95.

Copyright

Copyright: © 2025 Gyanesh Kumar Sahu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.