Janki Sahu¹, Sandhya Sahu¹, Tulsi Ram Sahu¹, Deepak Patel¹, Anjali², Harish Sharma³ and Gyanesh Kumar Sahu¹*

¹Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India
²Rungta Institute of Pharmaceutical Sciences, Kohka, Kurud, Bhilai, India
³School of Pharmacy, Anjaneya University, Raipur, India

*Corresponding Author: Dr. Gyanesh Kumar Sahu, Professor and Dean, Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India.

Received: November 29, 2024; Published: December 10, 2024

Abstract

Eczema is a widespread, recurrent, chronic inflammatory skin condition affecting millions worldwide. It is most common in early childhood and is characterized by skin redness and irritation. Emollients are the cornerstone of treatment, and anti-inflammatory medications like topical corticosteroids should be used to prevent and cure the illness. The Best Emollients for Eczema (BEE) study found that all emollient groups showed improvement in eczema symptoms during the 16-week primary outcome period. Atopic eczema can have a significant financial impact and can affect people of all ages and races. The diagnosis of eczema is based on the increase in total or serum IgE levels specific to allergies, with the term "intrinsic" (non-IgE-associated) AE coined to differentiate it from "extrinsic" (IgE-associated) forms.

Keywords:Eczema; Inflammatory; IgE

References

1. Kay J., et al. “The prevalence chádhood atopic eczema in a general population”. Journal of the American Academy of Dermatology 30 (1904): 35-39.
2. Langan SM., et al. “Atopic dermatitis”. Lancet 396 (2020): 345-360.
3. LePoidevin LM., et al. “A comparison of international management guidelines for atopic dermatitis”. Pediatric Dermatology 36 (2019): 36-65.
4. Bridgeman A. “Management of atopic eczema in the community”. Health Visitor 67 (1994): 226-227.
5. Forsdyke H and Watts J. “Skin care in atopic eczema”. 10 (1994): 36-40.
6. Burdette-Taylor S. “Eczema, ichthyosis, psoriasis: conditions of cornification”. Wound Management 41 (1995): 36-42.
7. Ridd M. “Emollients for children with eczema”. Dermatological Nursing4 (2022).
8. Shen S., et al. “Evaluation of Antioxidant Activity and Treatment of Eczema by Berberine Hydrochloride-Loaded Liposomes-in-Gel”. Molecules7 (2024): 1566.
9. Allen OG., et al. “Parent satisfaction with lotion, cream, gel and ointment emollient types: secondary analysis of the Best Emollients for Eczema study”. Clinical and Experimental Dermatology6 (2024): 573-577.
10. Hanot A., et al. “Adverse events from emollient use in eczema: a restricted review of published data”. Dermatology and Therapy 9 (2019): 193-208.
11. Thandar Y., et al. “Topical herbal medicines for atopic eczema: a systematic review of randomized controlled trials”. British Journal of Dermatology2 (2017): 330-343.
12. Liu J., et al. “Efficacy of a Chinese herbal medicine for the treatment of atopic dermatitis: a randomised controlled study”. Complementary Therapies in Medicine5 (2015): 644-651.
13. Zari ST and Zari TA. “A review of four common medicinal plants used to treat eczema”. Journal of Medicinal Plants Research24 (2015): 702-711.
14. Van Zuuren EJ., et al. “Emollients and moisturizers for eczema: abridged Cochrane systematic review including GRADE assessments”. British Journal of Dermatology5 (2017): 1256-1271.
15. Lopez Carrera YI., et al. “Epidemiology, diagnosis, and treatment of atopic dermatitis in the developing countries of Asia, Africa, Latin America, and the Middle East: a review”. Dermatology and Therapy4 (2019): 685-705.
16. Williams H., et al. “Is eczema really on the increase worldwide?”. Journal of Allergy and Clinical Immunology 4 (2008): 947-54.
17. Wollenberg A., et al. “ETFAD/EADV Eczema task force 2020 position paper on diagnosis and treatment of atopic dermatitis in adults and children”. Journal of the European Academy of Dermatology and Venereology12 (2020): 2717-2744.
18. Solman L., et al. “What’s new in atopic eczema? An analysis of systematic reviews published in 2016. Part 1: treatment and prevention”. Clinical and Experimental Dermatology4 (2019): 363.
19. Schmitt J., et al. “The Harmonising Outcome Measures for Eczema (HOME) statement to assess clinical signs of atopic eczema in trials”. Journal of Allergy and Clinical Immunology4 (2014): 800-807.
20. Shams K., et al. “What’s new in atopic eczema? An analysis of systematic reviews published in 2009- 2010”. Clinical and Experimental Dermatology6 (2011): 573-578.
21. Chang C., et al. “Treatment of eczema”. Clinical Reviews in Allergy and Immunology 33 (2007): 204-225.
22. Vermeulen FM., et al. “TREatment of Atopic eczema (TREAT) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries”. British Journal of Dermatology3 (2019): 492-504.
23. Siegels D., et al. “Systemic treatments in the management of atopic dermatitis: a systematic review and meta-analysis”. Allergy4 (2021): 1053-1076.
24. Hoare C and Williams H. “Systematic review of treatments for atopic eczema”. Health Technology Assessment (Winchester, England)37 (2000): 1-91.
25. Leung DY and Guttman-Yassky E. “Assessing the current treatment of atopic dermatitis: unmet needs”. Journal of Allergy and Clinical Immunology4 (2017): S47-48.
26. Osher GR., et al. “Efficacy of Over-the-Counter Moisturizers in Pediatric Atopic Dermatitis: An Update to a Systematic Review”. Current Dermatology Reports 25 (2024): 1-2.

Citation

Citation: Gyanesh Kumar Sahu., et al. “A Comprehensive Review on the Management of Eczema: Current Trends and Emerging Herbal Therapies". Acta Scientific Pharmaceutical Sciences 9.1 (2025): 11-16.

Copyright

Copyright: © 2025 Gyanesh Kumar Sahu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.