Formulation and Evaluation of Herbal Antifungal Cream
Ranvijay Bharti1, Shilpi Pal1, Nandini Prasad1, Yogesh Kumar1, B Joseph1, Harish Sharma2 and Gyanesh Kumar Sahu2*
1Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India
2Rungta Institute of Pharmaceutical Sciences, Kohka, Kurud, Bhilai, India
*Corresponding Author: Gyanesh Kumar Sahu, Dean and Professor, Rungta Institute of Pharmaceutical Sciences and Research, Kohka, Kurud, Bhilai, India.
Received:
April 08, 2024; Published: May 20, 2024
Abstract
A hydrogel is a three-dimensional network of polymers that is insoluble in water and can absorb bodily fluids in a biological setting. Such a polymer network is created via physical crosslinking, which includes ionic crosslinking, temperature and pH-dependent processes, and enzyme reactions, as well as chemical crosslinking mechanisms like optical polymerization. Chemical hydrogels are created by covalent forces, whereas physical hydrogels are formed by weak secondary forces. Hydrogels are made from a variety of synthetic and natural polymers. The most significant characteristics of hydrogels are swelling, mechanical characteristics, and biological characteristics, all of which have an impact on the hydrogel's morphology and structure. Hydrogen finds value in wound dressings, tissue engineering, contact lenses, and therapeutic drug release, among other medical applications, because of its water absorbing properties and structural resemblance to the extracellular matrix (ECM). We talk about hydrogels, types of hydrogels, their characteristics, and medical applications.
Keywords: Polymer; Hydrogel; Tissue Engineering
References
- Holzapfel BM., et al. “How smart do biomaterials need to be? A translational science and clinical point of view”. Advanced Drug Delivery Reviews4 (2013): 581-603.
- Chamkouri H and Chamkouri M. “A review of hydrogels, their properties and applications in medicine”. American Journal of Biomedical Science and Research 6 (2021): 485-493.
- El Sayed MM. “Production of Polymer Hydrogel Composites and Their Applications”. Journal of Polymers and the Environment 15 (2023): 1-25.
- Maitra J and Shukla VK. “Cross-linking in hydrogels-a review”. American Journal of Polymer Science 2 (2014): 25-31.
- Cao H., et al. “Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity”. Signal Transduction and Targeted Therapy1 (2021): 426.
- Xiao A., et al. “Strategies to design antimicrobial contact lenses and contact lens cases”. Journal of Materials Chemistry B 6.15 (2018): 2171-2186.
- Gyles DA., et al. “A review of the designs and prominent biomedical advances of natural and synthetic hydrogel formulations”. European Polymer Journal 88 (2017): 373-392.
- Vashist A., et al. “Recent advances in hydrogel based drug delivery systems for the human body”. Journal of Materials Chemistry B 2.2 (2014): 147-166.
- Omidian H., et al. “Advances in superporous hydrogels”. Journal of Controlled Release1 (2005): 3-12.
- Khandan A., et al. “Hydrogels: Types, structure, properties, and applications”. Biomaterials and Tissue Engineering 27 (2007): 143-169.
- Lanzalaco S and Armelin E. “Poly (N-isopropylacrylamide) and copolymers: A review on recent progresses in biomedical applications”. Gels4 (2017): 36.
- Pérez-Herrero E and Fernández-Medarde A. “Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy”. European Journal of Pharmaceutics and Biopharmaceutics 93 (2015): 52-79.
- Lavrador P., et al. “Stimuli‐responsive nanocomposite hydrogels for biomedical applications”. Advanced Functional Materials8 (2021): 2005941.
- Raza F., et al. “A review on recent advances in stabilizing peptides/proteins upon fabrication in hydrogels from biodegradable polymers”. Pharmaceutics 1 (2018): 16.
- Ding M., et al. “Multifunctional soft machines based on stimuli-responsive hydrogels: from freestanding hydrogels to smart integrated systems”. Materials Today Advances 8 (2020): 100088.
- Decroly G., et al. “Programmable stimuli-responsive actuators for complex motions in soft robotics: Concept, design and challenges”. InActuators 4 (2020): 131.
- Abrego CJ., et al. “Multiscale characterization of the mechanical properties of fibrin and polyethylene glycol (PEG) hydrogels for tissue engineering applications”. Macromolecular Chemistry and Physics1 (2022): 2100366.
- Ali A and Ahmed S. “Recent advances in edible polymer based hydrogels as a sustainable alternative to conventional polymers”. Journal of Agricultural and Food Chemistry27 (2018): 6940-6967.
- Singhal R and Gupta K. “A review: Tailor-made hydrogel structures (classifications and synthesis parameters)”. Polymer-Plastics Technology and Engineering1 (2016): 54-70.
- Xue X., et al. “Fabrication of physical and chemical crosslinked hydrogels for bone tissue engineering”. Bioactive Materials 12 (2022): 327-339.
- Mavila S., et al. “Intramolecular cross-linking methodologies for the synthesis of polymer nanoparticles”. Chemical Reviews3 (2016): 878-961.
- Lee JH. “Injectable hydrogels delivering therapeutic agents for disease treatment and tissue engineering”. Biomaterials Research1 (2018): 1-4.
- Neumann MG., et al. “The initiating radical yields and the efficiency of polymerization for various dental photoinitiators excited by different light curing units”. Dental Materials6 (2006): 576-584.
- Yahia S., et al. “Fortified gelatin-based hydrogel scaffold with simvastatin-mixed nanomicelles and platelet rich plasma as a promising bioimplant for tissue regeneration”. International Journal of Biological Macromolecules 225 (2023): 730-744.
- Decker C. “Light‐induced crosslinking polymerization”. Polymer International11 (2002): 1141-1150.
- Rao MA., et al. “Enzymes as useful tools for environmental purposes”. Chemosphere 107 (2014): 145-162.
- Coviello T., et al. “Polysaccharide hydrogels for modified release formulations”. Journal of Controlled Release1 (2007): 5-24.
- Kotla NG., et al. “Hyaluronic Acid‐Based Bioconjugate Systems, Scaffolds, and Their Therapeutic Potential”. Advanced Healthcare Materials20 (2023): 2203104.
- Xi W., et al. “Click chemistry in materials science”. Advanced Functional Materials18 (2014): 2572-2590.
- Chopin N., et al. “Design polysaccharides of marine origin: chemical modifications to reach advanced versatile compounds”. Current Organic Chemistry7 (2014): 867-895.
- Roppolo I., et al. “3D Printing of Self‐Healing Materials”. Advanced Materials (2023): 2305537.
- Berger J., et al. “Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications”. European Journal of Pharmaceutics and Biopharmaceutics1 (2004): 19-34.
- Hennink WE and van Nostrum CF. “Novel crosslinking methods to design hydrogels”. Advanced Drug Delivery Reviews 64 (2011): 223-236.
- Li Z and Lin Z. “Recent advances in polysaccharide‐based hydrogels for synthesis and applications”. Aggregate2 (2021): e21.
- Vedadghavami A., et al. “Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications”. Acta Biomaterialia 62 (2017): 42-63.
- Kavitha K., et al. “Chitosan polymer used as carrier in various pharmaceutical formulations: brief review”. International Journal of Applied Biology and Pharmaceutical Technology2 (2011): 249-258.
- Ruel-Gariepy E and Leroux JC. “In situ-forming hydrogels—review of temperature-sensitive systems”. European Journal of Pharmaceutics and Biopharmaceutics2 (2004): 409-426.
- Kondiah PJ., et al. “A review of injectable polymeric hydrogel systems for application in bone tissue engineering”. Molecules11 (2016): 1580.
- Koetting MC., et al. “Stimulus-responsive hydrogels: Theory, modern advances, and applications”. Materials Science and Engineering: R: Reports 93 (2015): 1-49.
- Peppas NA., et al. “Stimuli-sensitive hydrogels: ideal carriers for chronobiology and chronotherapy”. Journal of Biomaterials Science, Polymer Edition2 (2004): 125-144.
- Karimi M., et al. “pH‐Sensitive stimulus‐responsive nanocarriers for targeted delivery of therapeutic agents”. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology5 (2016): 696-716.
- Qureshi D., et al. “Environment sensitive hydrogels for drug delivery applications”. European Polymer Journal 120 (2019): 109220.
- Resende JF., et al. “Hydrogels produced from natural polymers: A review on its use and employment in water treatment”. Brazilian Journal of Chemical Engineering1 (2023): 23-38.
- Samrot AV., et al. “Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: A review”. International Journal of Biological Macromolecules 165 (2020): 3088-3105.
- Shaikh FM., et al. “Fibrin: a natural biodegradable scaffold in vascular tissue engineering”. Cells Tissues Organs4 (201308:333-346.
- Kumar AC and Erothu H. “Synthetic polymer hydrogels”. Biomedical applications of Polymeric Materials and Composites (2016): 141-162.
- Maitz MF. “Applications of synthetic polymers in clinical medicine”. Biosurface and Biotribology3 (2015): 161-176.
- Marín Cardona ES., et al. “A review of polyvinyl alcohol derivatives: promising materials for pharmaceutical & biomedical applications”. (2013).
- Chen H., et al. “Biocompatible polymer materials: role of protein–surface interactions”. Progress in Polymer Science11 (2008): 1059-1087.
- Ahmad Z., et al. “Versatility of hydrogels: from synthetic strategies, classification, and properties to biomedical applications”. Gels3 (2022): 167.
Citation
Copyright