Advances in Topical Drug Delivery System for the Impressive Management of Fungal Bugs
Abhay Pratap, Anupriya Kapoor, Ajay Kumar, Manisha Trivedi and
Shashi Kiran Misra*
School of Pharmaceutical Sciences, CSJM University, Kanpur, India
*Corresponding Author: Shashi Kiran Misra, Director, School of Pharmaceutical
Sciences, CSJM University, Kanpur, India.
Received:
April 30, 2024; Published: May 06, 2024
Abstract
Drug delivery systems show how a medicinal substance is delivered to the intended location to provide a therapeutic effect. These
days, fungi are responsible for an increasing number of ailments all over the world. Four types of infections may be distinguished:
cutaneous mycosis, subcutaneous mycosis, superficial mycosis, and systemic mycosis. It is believed by researchers that treating
these mycoses with only currently known antifungal agents would not be enough. A novel antifungal medication that acts on the
target locations must go through a protracted research process, several animal and human clinical tests and trials, development, and
regulatory approval before it can be introduced to the market. It is time-consuming, expensive, and likely to fail. As a result, changes
to the current medication delivery system have always been considered and are being sought in novel ways. Novel developments in
antifungal drug delivery systems have been created and managed to overcome the problems of dissolution, stability, bioavailability,
safety, and efficacy existing in conventional formulations and procedures by applying the understanding of pharmacodynamics and
pharmacokinetic principles. The four main categories of advancements in the delivery of antifungal medications include vesicular
systems, Nano particulate-based structures, colloidal carriers, and various drug delivery systems. Amphotericin B and other azole
types are examples of well-established therapeutic drugs for antifungal therapy that may be designed into many different carriers
and delivery systems that are tailored to the patient's sickness level and the affected area. New avenues for reducing therapeutic side
effects have been made possible by innovative antifungal drug delivery methods.
Keywords: Topical Delivery; Antifungal Drugs; Nanotechnology; Colloidal Carriers
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