Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 7 Issue 9

Positive Proteinuria Postpartum: To your Trocars, Set, Biopsy!

Ghita Yousfi1*, Wiame Rami1, Sara Ait Ghazi1, Basmat Amal Chouhani1, Ghita Elbardai, Laila Tahiri², Nadia Kabbali1, Hinde Elfatemi² and Tarik Sqalli Houssaini1

1Department of Nephrology, CHU HASSAN II DE FES, Morocco
2Department of Pathological Anatomy, CHU HASSAN II DE FES, Morocco

*Corresponding Author: Ghita Yousfi, Department of Nephrology, CHU HASSAN II DE FES, Morocco.

Received: August 18, 2023; Published: August 22, 2023

Abstract

Fourteen biopsies were performed postpartum, mean time 4.8 months (1-12), the indication for renal biopsy was proteinuria in 100% of patients with two patients with nephrotic syndrome, renal failure was present in 7 patients and hematuria in 6 patients. 4 patients had extrarenal signs (arthralgia in 2 patients and RAYNAUD's syndrome in 2 patients) absence of extrarenal signs in the rest of the patients. Diuresis was retained in 12 patients and anuria in 2 patients. The diagnosis was segmental and focal hyalinosis (HSF) in 5 patients or 35.7%, extramembranous glomerulonephritis in 2 patients or 14.3%, chronic glomerulonephritis in 2 patients or 14.3%, acute glomerulonephritis in 1 patient or 7.14%, membrano-proliferative glomerulonephritis in 1 patient or 7.14%, minimal glomerular lesion in 1 patient 7.14%, vasculitis in a patient 7.14%, 1 patient with shepherd's disease or 7.14%.

The evolution was marked by complete remission in 5 patients, partial remission in 2 patients, 5 patients progressed to end-stage chronic renal failure with hemodialysis, one patient in chronic renal failure with stationary renal function, one patient treatment in progress.

 Keywords: Preeclampsia; Proteinuria; Hematuria; Renal Failure; Renal Biopsy

References

  1. Kaze FF., et al. “Post-partum trend in blood pressure levels, renal function and proteinuria in women with severe preeclampsia and eclampsia in SubSaharan Africa: a 6-months cohort study”. BMC Pregnancy Childbirth 14 (2014): 134.
  2. C Domenger., et al. “Nephrology, CHU de Poitiers, Poitiers, France 2 Medical resuscitation, CHU de Poitiers, Poitiers, France”.
  3. “Frances Conti-Ramsden, Department of Women and Children’s Health, 10th Floor North Wing, St Thomas’ Hospital, Westminster Bridge Road, London SE1 7EH, UK Renal biopsy findings during and after pregnancy”.
  4. Selman Unverdi., et al. “Postpartum persistent proteinuria after preeclampsia: a single-center experience”. Wien Klin Wochenschr3-4 (2013): 91-95.
  5. Murakami S., et al. “Renal disease in women with severe preeclampsia or gestational proteinuria”. Obstetrics and Gynecology 96 (2000): 945-949.
  6. Day C., et al. “The role of renal biopsy in women with kidney disease identified in pregnancy”. Nephrology Dialysis Transplantation 1 (2008): 201-206.

Citation

Citation: Ghita Yousfi., et al. “Positive Proteinuria Postpartum: To your Trocars, Set, Biopsy!". Acta Scientific Pharmaceutical Sciences 7.9 (2023): 39-42.

Copyright

Copyright: © 2023 Ghita Yousfi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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