Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 7 Issue 8

Copper(II) Complexes of an N-pendent Cyanoethyl Derivative of a Tetraazamacrocyclic Ligand: Synthesis, Characterization and Antibacterial Studies

Suravi Dhar1, Saswata Rabi2, Pradip Paul1, Avijit Chakraborty1, Benu Kumar Dey1 and Tapashi Ghosh Roy1*

1Department of Chemistry, University of Chittagong, Chattogram, Bangladesh
2Department of Chemistry, Chittagong University of Engineering and Technology, Chattogram, Bangladesh

*Corresponding Author: Tapashi Ghosh Roy, Department of Chemistry, University of Chittagong, Chattogram, Bangladesh.

Received: June 06, 2023; Published: July 14, 2023


One of the isomers of the ligand Me6[14]ane, ‘tet-b’ upon reflux with acrylonitrile produced N-pendent derivative ‘tet-bx’ in which two cyano-ethyl groups were attached on less crowded two trans-N atoms. The reaction of copper(II) perchlorate hexahydrate with ‘tet-bx’ yielded six coordinated octahedral reddish-purple [Cu(tet-bx)(ClO4)2]. The axial substitution reactions of [Cu(tet-bx)(ClO4)2] with KX (X= SCN, NO3, Cl, Br or I) and NaNO2 afforded six coordinated blue [Cu(tet-bx)(NCS)(ClO4)] and [Cu(tet-bx)(NO2)(H2O)]ClO4; red [Cu(tet-bx)(NO3)(H2O)]ClO4 and [Cu(tet-bx)Cl(H2O)]ClO4 and purple [Cu(tet-bx)Br(H2O)]ClO4 and [Cu(tet-bx)I(H2O)]ClO4. The complexes were characterized on the basis of elemental, spectroscopic, magnetochemical and conductometric analysis. The antibacterial activities of the concerned ligand and its copper(II) complexes have been tested against four selected bacteria.

 Keywords: N-pendant Tetraazamacrocyclic Ligand; Copper (II) Complexes; Spectroscopic Studies; Antibacterial Activities


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Citation: Tapashi Ghosh Roy., et al. “Copper(II) Complexes of an N-pendent Cyanoethyl Derivative of a Tetraazamacrocyclic Ligand: Synthesis, Characterization and Antibacterial Studies". Acta Scientific Pharmaceutical Sciences 7.8 (2023): 33-41.


Copyright: © 2023 Tapashi Ghosh Roy., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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