Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Case Review Volume 7 Issue 5

Cocrystals: A New Form of Solid with Improved Physico-chemical Properties

RR Thenge*

Dr. Rajendra Gode College of Pharmacy, Malkapur, Maharashtra, India

*Corresponding Author: RR Thenge, Dr. Rajendra Gode College of Pharmacy, Malkapur, Maharashtra, India.

Received: February 27, 2023; Published: April 24, 2023


Co-crystals are defined as structurally homogeneous/heterogeneous crystalline solids that include drug and coformer in specific stoichiometric proportions. The discrete neutral molecular reactants that make up co-crystals are solids at room temperature. According to this definition of co-crystals, a pharmaceutical co-crystal is a mixture in which one of the co-crystals’ elements serves as an active medicinal ingredient and the other elements serve as coformers. An active drug hydrate is not a co-crystal, as is evident from the statement, but a solid-state drug hydrate is co-crystalline with a coformer to produce a co-crystal [1]. The pharmaceutical sector currently places a lot of attention on co-crystal methods. Pharmaceutical co-crystals can successfully enhance the drug substance’s solubility, dissolving profile, bioavailability and physical stability, in addition to other crucial features such as flowability, chemical stability, compressibility and hygroscopicity [2].


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Citation: RR Thenge. “Cocrystals: A New Form of Solid with Improved Physico-chemical Properties". Acta Scientific Pharmaceutical Sciences 7.5 (2023): 20-21.


Copyright: © 2023 RR Thenge. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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