Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Review Article Volume 7 Issue 4

Nutritional and Pharmacological Potential of Edible Mushroom

Rakesh Sahu1*, Kuleshwar Sahu1,2, Rashmi Chanda1,3, Khemendra Kumar Chaturvedi1,4, Bhaskar Sahu1,5 and Himanshu Chaursia1,6

1Department of Pharmacology, Sanjivani Institute of Pharmacy, Ganiyari, Bilaspur, India
2Department of Pharmacology, School of Pharmacy, CEC, Bilaspur, Chhattisgarh, India
3Royal College of Pharmacy, Raipur, Chhattisgarh, India
4Department of Pharmaceutics, JK College of Pharmacy, Bilaspur, Chhattisgarh, India
5Department of pharmaceutical Chemistry, Columbia College of Pharmacy, Raipur, Chhattisgarh, India
6Department of Pharmacy, Quantum School of Health Science, Roorkee, Dehradun Uttarakhand, India

*Corresponding Author: Rakesh Sahu, Assistant Professor, Department of Pharmacology, Sanjivani Institute of Pharmacy, Ganiyari, Bilaspur, India.

Received: February 20, 2023; Published: March 28, 2023

Abstract

Mushrooms have influenced human development in many ways, including food, medicine,culture, and religion. Mushrooms are mostly consumed for their taste and texture. They have recently gained favour as a healthy meal and a tool for drug development. According to several studies, edible mushrooms have several medicinal properties including, anti-cancer, immunomodulatory, cardiovascular, hepatoprotective, Neuroprotective hypolipidemic, antiviral, antibacterial, antiparasitic, and antidiabetic activities. Mushrooms are high in proteins, minerals, polysaccharides, unsaturated fatty acids, and secondary metabolites, making them a great source of nutrition. In this review, the contents and nutritional values of edible mushrooms were thoroughly investigated. The utilisation of edible mushrooms as prospective therapeutic proxies, as well as components found in edible mushrooms that have bioactive capabilities, such as polyphenolic chemicals and antioxidant activity, were also discussed. Mushrooms provide several health benefits, including the prevention and treatment of neurological disorders like Parkinson's disease, Alzheimer's disease, and multiple sclerosis and in addition to the reduction of stroke risk. They are also utilised to decrease the chances of cancer progression due to their anticancer effects. Review and evaluation of recent studies on the impact of using edible mushrooms in the production of functional foods, along with the effects on the physiological, organoleptic, and nutritional value of the resulting products. Using edible mushrooms as a key source of functional components in food products, according to contemporary socioeconomic trends, could serve as a natural adjuvant for the prevention and treatment of several lifestyle-related diseases. This information could be useful in the development of food products with medical properties, mushroom is especially important for the medication management profession, which originated from the fusion of the food and pharmaceutical professions. Additionally, this review paper could be very useful to scientists, researchers, and doctors in the health sector in reducing the progression of several lifestyle diseases, neurodegenerative disorders, and autoimmune disorders.

Keywords: Edible Mushroom; Medicinal Value; Nutritional Value; Drug Development; Therapeutic Agent

References

  1. Friedman M. “Mushroom polysaccharides: chemistry and antiobesity, antidiabetes, anticancer, and antibiotic properties in cells, rodents, and humans”. Foods4 (2016): 80.
  2. Sharpe E., et al. “Comparison of antioxidant activity and extraction techniques for commercially and laboratory prepared extracts from six mushroom species”. Journal of Agriculture and Food Research 4 (2021): 100130.
  3. Cheung L., et al. “Antioxidant activity and total phenolics of edible mushroom extracts”. Food chemistry2 (2003): 249-255.
  4. Kalaras MD., et al. “Effects of postharvest pulsed UV light treatment of white button mushrooms (Agaricus bisporus) on vitamin D2 content and quality attributes”. Journal of Agricultural and Food Chemistry1 (2012): 220-225.
  5. Zhang M., et al. “Mushroom polysaccharide lentinan for treating different types of cancers: A review of 12 years clinical studies in China”. Progress in Molecular Biology and Translational Science 163 (2019): 297-328.
  6. Roupas P., et al. “The role of edible mushrooms in health: Evaluation of the evidence”. Journal of Functional Foods 4 (2012): 687-709.
  7. Manikandan K. “Nutritional and medicinal values of mushrooms”. Mushrooms Cultivation, Marketing and Consumption (2011): 11-14.
  8. Ho L-H., et al. “Edible mushroom: nutritional properties, potential nutraceutical values, and its utilisation in food product development”. An Introduction to Mushroom (2020): 10.
  9. Atila F., et al. “The nutritional and medical benefits of Agaricus bisporus: a review”. Journal of Microbiology, Biotechnology and Food Sciences 2021 (2021): 281-286.
  10. Khursheed R., et al. “Therapeutic potential of mushrooms in diabetes mellitus: Role of polysaccharides”. International Journal of Biological Macromolecules 164 (2020): 1194-205.
  11. Enkhmaa B., et al. “Lifestyle changes: effect of diet, exercise, functional food, and obesity treatment on lipids and lipoproteins”. Endotext (2018).
  12. Chaturvedi V., et al. “Medicinal mushroom: Boon for therapeutic applications”. 3 Biotech 8 (2018): 334.
  13. Smiderle F., et al. “Exopolysaccharides, proteins and lipids in Pleurotus pulmonarius submerged culture using different carbon sources”. Carbohydrate Polymers 1 (2012): 368-376.
  14. Novaes MRCG., et al. “The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicine”. Clinics 66 (2011): 2133-2139.
  15. Shin A., et al. “Dietary mushroom intake and the risk of breast cancer based on hormone receptor status”. Nutrition and Cancer4 (2010): 476-483.
  16. Soares AA., et al. “Hepatoprotective effects of mushrooms”. Molecules7 (2013): 7609-7630.
  17. Shankar NG., et al. “Hepatoprotective and antioxidant effects of Commiphora berryi (Arn) Engl bark extract against CCl4-induced oxidative damage in rats”. Food and Chemical Toxicology9 (2008): 3182-3185.
  18. Kang H-W. “Antioxidant and anti-inflammatory effect of extracts from Flammulina velutipes (Curtis) Singer”. Journal of the Korean Society of Food Science and Nutrition8 (2012): 1072-1078.
  19. Nikolovska-Nedelkoska D., et al. “Screening of antibacterial and antifungal activities of selected Macedonian wild mushrooms”. Zbornik Matice srpske za prirodne nauke 124 (2013): 333-340.
  20. Kashina S., et al. “Extracts from Flammulina velutipes inhibit the adhesion of pathogenic fungi to epithelial cells”. Pharmacognosy Research 8 (2016): S56.
  21. Saito M and Kuwahara S. “Enantioselective total synthesis of enokipodins A–D, antimicrobial sesquiterpenes produced by the mushroom, Flammulina velutipes”. Bioscience, Biotechnology, and Biochemistry2 (2005): 374-381.
  22. Hsieh KY., et al. “Oral administration of an edible‐mushroom‐derived protein inhibits the development of food‐allergic reactions in mice”. Clinical and Experimental Allergy11 (2003): 1595-1602.
  23. Barickman TC., et al. “Selenium influences glucosinolate and isothiocyanates and increases sulfur uptake in Arabidopsis thaliana and rapid-cycling Brassica oleracea”. Journal of Agricultural and Food Chemistry1 (2013): 202-209.
  24. Carroll MC. “The complement system in regulation of adaptive immunity”. Nature Immunology10 (2004): 981-986.
  25. Shin K-S., et al. “Production of Anti-Complementary Exopolysaccharides from Submerged Culture of Flammulina velutipes”. Food Technology and Biotechnology 3 (2007).
  26. Pizzino G., et al. “Oxidative stress: harms and benefits for human health”. Oxidative Medicine and Cellular Longevity (2017).
  27. Barros L., et al. “Optimization of the determination of tocopherols in Agaricus sp. edible mushrooms by a normal phase liquid chromatographic method”. Food Chemistry4 (2008): 1046-1050.
  28. Shaffique S., et al. “Current knowledge of medicinal mushrooms related to anti-oxidant properties”. Sustainability14 (2021): 7948.
  29. Sánchez C. “Bioactives from mushroom and their application”. Food Bioactives: Springer (2017): 23-57.
  30. Krainc D. “Clearance of mutant proteins as a therapeutic target in neurodegenerative diseases”. Archives of Neurology4 (2010): 388-392.
  31. Noorbakhsh F., et al. “Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology”. Trends in Neurosciences2 (2009): 88-100.
  32. Yadav SK., et al. “A mechanistic review on medicinal mushrooms-derived bioactive compounds: Potential mycotherapy candidates for alleviating neurological disorders”. Planta Medica16 (2020): 1161-1175.
  33. Wachtel-Galor S., et al. “Ganoderma lucidum (‘Lingzhi’), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study”. British Journal of Nutrition 2 (2004): 263-269.
  34. Li EK., et al. “Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double‐blind, randomized, placebo‐controlled pilot trial”. Arthritis Care and Research7 (2007): 1143-1150.

Citation

Citation: Rakesh Sahu., et al. “Nutritional and Pharmacological Potential of Edible Mushroom". Acta Scientific Pharmaceutical Sciences 7.4 (2023): 17-28.

Copyright

Copyright: © 2023 Rakesh Sahu., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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