Isolation and Characterization and Cell-line Toxicity Study of Novel Biopolymer from Naturally Occurring Seeds
Sushant Kumar1*, Swarnima Pandey2 and Anita Singh3
1Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India
2Department of Pharmacy, Hygia Group of Institutions, UP, India
3Research Associate, Dr. SK Research and Development laboratory, Dewa, UP, India
*Corresponding Author: Sushant Kumar, Faculty of Pharmacy, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.
July 28, 2022; Published: August 22, 2022
The aim of this research was to isolate and characterize the novel biopolymer from Phaseolus vulgaris seeds. The biopolymer was isolated by simplified and economical process and analysed for different physico-chemical and spectral properties. The isolated biopolymer appears as free flowing powder. The isolation procedures were optimized by repeating it for six times and thus were found to be economical and reproducible in nature. The different functional groups like presence of hydroxyl, alkanes and alkenes, carboxylic acid which confirms its polymeric nature. The other groups like aromatic ring at, ketone were found to be present in the FTIR spectra, NMR and mass spectra. The study finds that the isolated biopolymer from Phaseolus vulgaris seeds contains unusual inherent stabilizer and cum retardant capabilities that can be exploited to develop a lamotrigine-loaded bionanosuspension for long-term administration of drug candidate.
Keywords: Biopolymer; Biomaterial; SEM; Mass Spectra; FTIR Spectra; Economical
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