Anurag Kumar Verma¹*, Rajneesh Kumar Gupta² and Amresh Gupta³

¹Research Scholar, Goel Institute of Pharmacy and Sciences, Lucknow (UP), India
²Faculty, Goel Institute of Pharmacy and Sciences, Lucknow (UP), India
³Faculty, Goel Institute of Pharmacy and Sciences, Lucknow

*Corresponding Author: Anurag Kumar Verma, Research Scholar, Goel Institute of Pharmacy and Sciences, Lucknow (UP), India.

Received: May 30, 2022; Published: June 24, 2022

Abstract

Nanoemulsion is submicron-sized colloidal particulate phase that is thermodynamically and kinetically stable isotropic dispersions which is made up of two immiscible liquids- water and oil. It is stabilized by an interfacial film made by efficient surfactant and co-surfactant to form a homogenous phase. Sulfamethoxazole is a 1, 2-oxazole moiety with a methyl group at the position 5 and a 4-aminobenzenesulfonamido group at the 3^rd position. It functions as an antibacterial, anti-microbial etc. This systematic review emphasizes on nanoemulsion’s preparation methods, merits and demerits and uses as incorporated anti-bacterial agent Sulfamethoxazole. Sulfamethoxazole relates to sulfonamide category that blocks the folate synthesis in microbial organisms i.e., bacteria. Sulfamethoxazole accomplishes this by blocking the action of enzyme dihydropteroate synthase which antagonizes p-aminobenzoic acid (PABA) during the formation of dihydrofolate. It includes various methods to prepare nanoemulsion i.e., microfludization, solvent evaporation etc. Nanoemulsion has multiples of advantages in terms of better skin penetration power, non-irritant to mouth etc over other dosage forms. It is suitable for topical, oral and parenteral use. This study concludes, anyone method can be chosen from different techniques to formulate sulfamethoxazole nanoemulsion and can be used in numerous treatments. It has better skin permeability power that makes it excellent.

Keywords: Nanoemulsion; Sulfamethoxazole; Antibacterial; Plasticizer; Review

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Citation

Citation: Anurag Kumar Verma., et al. “Antibacterial - Sulphamethoxazole Nanoemulsion: A Systematic Review". Acta Scientific Pharmaceutical Sciences 6.7 (2022): 37-41.

Copyright

Copyright: © 2022 Anurag Kumar Verma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.