The Significance of COVID-19 Vaccine Booster Dose. A Comparative Review
Mohamed Raslan1, Eslam MS1, Sara AR1 and Nagwa A Sabri2*
1Drug Research Centre, Cairo, Egypt
2Department of Clinical Pharmacy, Faculty of Pharmacy- Ain Shams University, Cairo, Egypt
*Corresponding Author: Nagwa A Sabri, Department of Clinical Pharmacy, Faculty of Pharmacy- Ain Shams University, Cairo, Egypt.
March 16, 2022; Published: April 07, 2022
Background: The COVID-19 epidemic affects practically every aspect of human activity. The pandemic effect will continue until development of proper vaccine that neutralize different emerging viral variants.
Discussion: Different studies showed an advantage for COVID-19 vaccine third “booster” dose regarding decreased infection rates, hospitalization rates, and morality rates. Furthermore, booster doses showed an enhanced neutralizing antibodies against new emerging Omicron variant. Absolute vaccine effectiveness for BioNTech/Pfizer (BNT162b2) or Moderna (mRNA-1273) booster ranged from 94 to 97 percent. Besides, the 10-fold decrease in infection rate for the boosted with BNT162b2.
Conclusion: It can be concluded that booster doses of COVID-19 vaccine showed beneficial and significant positive effects that we are in need nowadays to overcome the spread of new emerging variants, reducing infection rates, and the burden on health care facilities.
Keywords: COVID-19; Omicron; BioNTech/Pfizer Vaccine; AstraZeneca ChAdOx1
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