Hawa Alsadi¹*, Mustafa Alsadi², Soad Belhaj¹ and Dheba Mohammed Abobaker³

¹Chemistry Department, Faculty of Education, Elmergib University, Alkhums Libya
²Food and Drug Control Center, Alkhums, Libya
³Chemistry Department, Science College, Alzawia University, Alzawia Libya

*Corresponding Author: Hawa Alsadi, Chemistry Department, Faculty of Education, Elmergib University, Alkhums Libya.

Received: March 10, 2022; Published: March 31, 2022

Abstract

The Phytoconstituents of ethanolic/aqueous crude extract of leaves of P. graveolens was, screened qualitatively and quantitatively as well tested against some sorts of pathogenic bacteria. And the revealed results were by the Qualitative detection of those components such as Tannins, Saponins, Terpenoids, Volatile Oils, Flavonoids, Phenols, Aryl-amines, Alkaloids, Reducing Sugars, Glycosides and Amines, are varied in its presence in the extract between abundance, medium and few in existence. As for the Quantitative detection of the extract, the results were for flavonoids, saponins, alkaloids and polysaccharides 63.4, 60.3, 53.2 and 48 %, respectively. Besides, the bioactivity of ethanolic/aqueous crude extract of leaves of P. graveolens was tested against each of Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and results revealed 17, 14, 12 and 15 mm respectively.

Keywords: Phytoconstituents; Pelargonium graveolens; Qualitatively and Quantitatively Screening; Antibacterial

References

1. Pelargonium graveolens. “Germplasm Resources Information Network (GRIN)”. Agricultural Research Service (ARS), United States Department of Agriculture (USDA). (2007).
2. Pandey AK., et al. “Essential Oils: Sources of Antimicrobials and Food Preservatives”. Frontiers in Microbiology 7 (2017): 2161.
3. Akhtar BD and Azam T. “Antimicrobial activity of essential oils extracted from medicinal plants against the pathogenic microorganisms: A review”. Biological Sciences and Pharmaceutical Research 2 (2014): 1-7.
4. Roeschenbleck J., et al. “Phylogenetics, character evolution and a subgeneric revision of the genus Pelargonium (Geraniaceae)”. Phytotaxa 2 (2014): 31-76.
5. Saraswathi J., et al. “Phytopharmacological importance of Pelargonium species”. Journal of Medicinal Plant Research 13 (2011): 2587-2598.
6. TLC Reagents and Detection Methods - Physical and Chemical Detection Methods: Fundamentals, Reagents, I, Vol 1a, H. Jork, W. Funk, W. Fishcer, and H. Wimmer, Wiley, NY, 1990. Practice of Thin Layer Chromatography, 3^rd edition, J.C. Touchstone, Wiley-Interscience, NY (1992).
7. TLC Reagents and Detection Methods - Physical and Chemical Detection Methods: Activation Reactions, Reagent Sequences, Reagents, II, Vol 1b, H. Jork, W. Funk, W. Fishcer, and H. Wimmer, Wiley, NY (1994).
8. E Stahl. Springer-Verlag, NY. Thin Layer Chromatography, 2^nd edition (1969).
9. Medicinal Plants And traditional Medicine In Africa, (Ibadan Nigeria: Spectrum Books, (1993): 191-289.
10. G Trease and W Evans. “Pharmacognosy”. (11^th ed), ( London: Bailliere) (1989): 45-50.
11. J Harborne. “Phytochemical methods”. (London: Chapman and Hall, (1973): 49-88.
12. Talukdar A and Chaudhary B. “Phytochemical Screening of ethanolic extracts of Rubia Cordiofolia”. Pharmaceutical and Biological Sciences 4 (2010): 530-536.
13. Boham BA., et al. “Flavonoids and condensed tannins from leaves of Hawaiian vaccinium vaticulatum and V. calycinium”. Pacific Sciences 48 (1974): 458-463.
14. Obdoni Bo and Ochuko PO. “Phytochemical studies and comparative efficacy of the crude extracts of some Homostatic plants in Edo and Delta States of Nigeria”. Global Journal of Pure and Applied Sciences 8 b (2001): 203-208.
15. Harborne JB. “Phytochemical methods, London”. Chapman and Hall, Ltd. (1973): 49-188.
16. Ahmed HM and Al-Zubaidy AMA. “Exploring Natural Essential Oil Components and Antibacterial Activity of Solvent Extracts from Twelve Perilla Frutescens L. Genotypes”. Arabian Journal of Chemistry 13 (2020): 7390-7402.
17. Elegbede JA., et al. “Silver-Gold Alloy Nanoparticles Biofabricated by Fungal Xylanases Exhibited Potent Biomedical and Catalytic Activities”. Biotechnology Progress 35 (2019): e2829.
18. Balouiri M., et al. “Antifungal Activity of Bacillus Spp. Isolated from Calotropis Procera AIT. Rhizosphere against Candida Albicans”. Asian Journal of Pharmaceutical and Clinical Research 8 (2015): 213-217.
19. El Barnossi A., et al. “Antifungal Activity of Bacillussp. Gn-A11-18isolated from Decomposing Solid Green Household Waste in Water and Soil against Candida Albicans and Aspergillus Niger”. E3S Web Conf. 150 (2020): 02003.
20. Yang L., et al. “Durable antibacterial cotton fabrics based on natural borneol-derived Anti-MRSA agents”. Advanced Healthcare Materials 9 (2009): e2000186.
21. Pinto, R. “Estudo da atividade antibacteriana da Carvona e seus derivados”. Dissertacão de Mestrado. Universidade da Beira Interior, Covilha, Portugal (2014).
22. Mativandlela SPN., et al. “Antibacterial, antifungal and antitubercular activity of (the roots of) Pelargonium reniforme (CURT) and Pelargonium sidoides (DC) (Geraniaceae) root extracts”. South African Journal of Botany 72 (2006): 232-237.

Citation

Citation: Hawa Alsadi., et al. “Preliminary Phytoconstituents Screening and Antibacterial Activities of Pelargonium graveolens Leave Extract”.Acta Scientific Pharmaceutical Sciences 6.4 (2022): 40-46.

Copyright

Copyright: © 2022 Hawa Alsadi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.