Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Short Communication Volume 6 Issue 4

Genetic Variations of V3 and C3 Regions in Gp120 Protein of HIV-1 Env Gene

Hari Om Singh

Senior Director of Product Management, China

*Corresponding Author: Hari Om Singh, Senior Director of Product Management, China.

Received: April 26, 2021; Published: March 30, 2022


HIV-associated neurocognitive disorder (HAND) is an important cause of morbidity of HIV patients. The development of neurological disease among individuals having an HIV infection is variable. The env sequences of HIV-1 are important for cell entry and neurotropism. The env sequences vary among individuals having HIV infection. Hence the development of neurotoxicity differs among individuals with HIV infection. So far, none of the studies reported the mechanism of neurotoxicity in astrocytes. Hence we comprehended the genetic profile of the gp120 protein of HIV-1 env gene which influences the pathogenesis of neurocognitive diseases.



Citation: Hari Om Singh. “Genetic Variations of V3 and C3 Regions in Gp120 Protein of HIV-1 Env Gene". Acta Scientific Pharmaceutical Sciences 6.4 (2022): 39.


Copyright: © 2022 Hari Om Singh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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