Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Review Article Volume 5 Issue 11

Variant Under Investigation (VUI) and Severity of COVID-19 Third Wave. Is there a Correlation?

Sara AS1,2, Mohamed Raslan1,2, Eslam MS2 and Nagwa A Sabri1*

1Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt
2Drug Research Centre, Cairo, Egypt

*Corresponding Author: Nagwa A Sabri, Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Received: August 24, 2021; Published: October 23, 2021

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Abstract

Coronavirus (COVID-19) was introduced into society by the end of 2019, and there have already been over 160 million infections and 3.5 million fatalities as a result of it. Sustainable and non-declinable waves of covid-19 may result in different viral mutations and the emergence of different variants. The second wave as well as the third wave showed to be highly spreadable and in some countries mortality rates were higher in the third wave. Different variants emerged and were contributory in the second wave of covid-19 like 501Y.V2 in South Africa. Besides, in Spain the B.1.1.7 strain which is highly transmissible was contributory for the third wave. Moreover, by the end of May 2021 a new variant VUI-21MAY-02 (C.36.3) was discovered in United Kingdom which has an Egyptian origin and no proven evidence that it contributes to high incidences or increase case severities. Furthermore, mortality rates in Egypt showed to be significantly higher than the worldwide average mortality rates, indicating the need for more attention regarding protective measures, social distancing, and other precautionary procedures.

Keywords: Coronavirus Disease 2019; Severe Acute Respiratory Syndrome Coronavirus 2; Third Wave; Immunization; C.36.3 Variant

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References

  1. Rothan HA and Byrareddy SN. “The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak”. Journal of Autoimmune 109 (2020): 102433.
  2. Villoutreix BO., et al. “In silico investigation of the new UK (B.1.1.7) and South African (501y.v2) SARS-CoV-2 variants with a focus at the ace2–spike rbd interface”. International Journal of Molecular Sciences 22 (2021): 1-13.
  3. Deif AS and El-Naggar SA. “Modeling the COVID-19 spread, a case study of Egypt”. Journal of the Egyptian Mathematical Society 1 (2021): 13.
  4. https://covid19.who.int/region/emro/country/eg
  5. Wang C., et al. “COVID-19 in early 2021: current status and looking forward”. Signal Transduction and Targeted Therapy 6 (2021): 114.
  6. https://www.gov.uk/government/news/confirmed-cases-of-covid-19-variants-identified-in-uk
  7. Public Health England (PHE). SARS-CoV-2 variants of concern and variants under investigation in England, Technical briefing 13, 27 May 2021, This briefing provides an update on previous briefings up to 22 May (2021).
  8. Alfredo Maria Gravagnuolo., et al. “Epidemiological Investigation of New SARS-CoV-2 Variant of Concern 202012/01 in England”. medRxiv (2021).
  9. Waasila Jassat., et al. “Increased mortality among individuals hospitalised with COVID-19 during the second wave in South Africa”. medRxiv (2021).
  10. Hye Seong., et al. “Comparison of the second and third waves of the COVID-19 pandemic in South Korea: Importance of early public health intervention”. International Journal of Infectious Diseases 104 (2021): 742-745.
  11. Vicente Soriano., et al. “Third wave of COVID-19 in Madrid, Spain”. International Journal of Infectious Diseases 107 (2021): 212-214.
  12. Weekly epidemiological update on COVID-19 - 1 June (2021).
  13. https://covid19.who.int/region/emro/country/eg
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Citation

Citation: Nagwa A Sabri., et al. “Variant Under Investigation (VUI) and Severity of COVID-19 Third Wave. Is there a Correlation?". Acta Scientific Pharmaceutical Sciences 5.11 (2020): 55-58.




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