Abstract

Productive targeted drug delivery systems are a massive construct from an extended time, however it’s been stricken by the advanced chemistry that’s concerned within the development of latest system. To overcome these problems, significant step have been taken in invention of nanosponges. Nanosponges are the tiny mesh like structure in which large variety of drugs can be filled. These have inclusion and non-inclusion behavior and have high solubility for poor soluble drugs. These little sponges will flow into round the body till they realize binding surface and begins to unleash the drug. They can load both hydrophobic and hydrophilic drugs. They are simple to produce and are biologically safe. They can load each hydrophobic and hydrophilic medicine. They will be ready by cross linking differing kinds of cyclodextrins with a cross linker. Nanosponge technology has been explored for numerous applications like sustained unharness drug delivery system and delivery of medicine into the oral, epithelial duct further as topical routes. Nanosponges also can be used for unharness of enzymes, vaccines, proteins, antibodies and as a carrier for biocatalysts.

Keywords: Nanosponges; Cross Linking Agent; Cyclodextrins

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Citation

Citation: Tiwari Shailee Vijay., et al. “Nanosponges: An Innovative Class of Drug Delivery System - Review". Acta Scientific Pharmaceutical Sciences 5.11 (2020): 09-18.

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Copyright: © 2020 Tiwari Shailee Vijay., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.