Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 5 Issue 10

Essential Oil Composition and Antimicrobial Activities of Lavandula pubescens, Marrubium vulgare and Meriandra bengalensis from Yemen

Yani AA1, Eldahshan OA2,3*, Hassan SA4, Elwan ZA4 and Ibrahim HM1

1Biology Department, Botany Section, Faculty of Science, Sanaa University, Yemen
2Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Egypt
3Center for Drug Discovery Research and Development, Ain Shams University, Egypt
4Botany Department, Faculty of Science, Ain Shams University Cairo, Egypt

*Corresponding Author: Eldahshan OA, Faculty of Pharmacy, Department of Pharmacognosy, Ain Shams University, Cairo, Egypt.

Received: August 02, 2021; Published: September 18, 2021


  In Yemen, family Lamiaceae is one of the most important families due to its use in folk medicine and for the commercial production of essential oils. In this study, three Lamiaceae plants; Lavandula pubescens Decne, Marrubium vulgare L. and Meriandra bengalensis (Roxb.) Benth, were chemically investigated by GC/MS as well as their antimicrobial activity was assessed using agar-well diffusion method. The major compounds in Lavandula pubescens oil were carvacrol (54.98%), thymol methyl ether (12.15%) and Z-caryophyllene (4.47%), while those of Marrubium vulgare were Z-caryophyllene (10.95%), octadecanol (10.44%) and α-bisabolene (9.72%). Meriandra bengalensis contained camphor (64.87%) as a major compound with 1,8 cineole (12.16%) and camphene (11.96%). The strongest antimicrobial activity was observed in Lavandula pubescens against Klebsielle pneumoniae (1.95 μL/mL) which is higher than that of gentamycin, Enterobacter cloacae (0.98 μL/mL), and Bacillis subtilis (0.49 μL/mL) that are similar in activity to that of standards (gentamycin and ampicillin). Oils of Marrubium vulgare L. and Meriandra bengalensis exhibited a range of activities between weak and none. Our result concludes that Lavandula pubescens possess pronounced antimicrobial activity against Klebsielle pneumoniae, Enterobacter cloacae and Bacillis subtilis giving it a highly medicinal impact value to be further studied in vivo against different types of microbial infectious diseases

Keywords: Lamiaceae; Volatile Oil; Antimicrobial Activity


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Citation: Eldahshan OA., et al. “Essential Oil Composition and Antimicrobial Activities of Lavandula pubescens, Marrubium vulgare and Meriandra bengalensis from Yemen". Acta Scientific Pharmaceutical Sciences 5.10 (2021): 50-58.


Copyright: © 2021 Eldahshan OA., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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