Drug Resistance in Triple-Negative Breast Cancer: Strategies to Overcome
Md Abdus Subhan*
Department of Chemistry, ShahJalal University of Science and Technology, Bangladesh
*Corresponding Author: Md Abdus Subhan, Department of Chemistry, ShahJalal University of Science and Technology, Bangladesh.
Received:
May 06, 2021; Published: June 03, 2021
Abstract
Triple-negative breast cancer has fewer treatment options than other types of invasive breast cancers. This is because of the lack of estrogen, progesterone receptors and HER2 proteins, which limits the targeted therapy for TNBC. The main therapeutic options are chemotherapy and radiation therapy. However, these treatments are associated with drug resistance and ultimately poor prognosis and reduced survival. It is thus vital to overcome drug resistance and develop targeted therapy for TNBC for enhanced prognosis and prolonged survival. This mini review discusses drug resistance and targeted therapy for TNBC.
Keywords: Breast Cancer; Drug Resistance; Estrogen
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