Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Review Article Volume 5 Issue 2

Therapeutic Strategies for Novel Corona Virus Disease (COVID-19): A Comprehensive Review

Manoj Gadewar*, Mohd Kafeel and Dharmender

Department of Pharmacology, School of Medical and Allied Sciences, K.R. Mangalam University, Gurugram, Haryana, India

*Corresponding Author: Manoj Gadewar, Professor, Department of Pharmacology, School of Medical and Allied Sciences, K.R. Mangalam University, Gurugram, Haryana, India.

Received: December 08, 2020; Published: January 11, 2021

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Abstract

  A newly emerged Human Coronavirus (HCoV) was reported in month of Dec 19 in Wuhan city of China (COVID-19). Due to high virulence ability and resistance of corona virus, several studies were carried out to screen existing drugs like antiviral, anti-malarial and anti-tubercular as potential targets for the treatment of disease. Therefore, its essential to develop an effective treatment strategy to control the virus spread and prevent the disease. In this review Here, we have reported the novel approaches and strategies that were used to treat and prevent COVID infection. Although it seems that antiviral drugs, antiprotozoal, antibacterial drug, an antimalarial drug, and immunosuppressive drug are effective in improving clinical manifestation, there is no definite treatment protocol. Lymphocytopenia, excessive inflammation, and cytokine storm followed by acute respiratory distress syndrome are still unresolved issues that making the disease more severe. Various herbal drugs derived from Indian traditional medicines, Chinese herbals medicine/traditional Chinese medicine (CHM/TCM) were used to prevent the progression of disease.

Keywords: COVID-19; SARS-CoV-2; World Health Organization (WHO)




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