Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Short Communication Volume 5 Issue 1

Managements of COVID-19 by Curcumin

Ahmed M Abd-Alkhalek1 and Omayma A Eldahshan2*

1Faculty of Medicine, Al-Azhar University, Cairo, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

*Corresponding Author: Omayma A Eldahshan, Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Received: December 10, 2020; Published: December 22, 2020

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  Curcumin, the polyphenolic compound in turmeric exhibited versatile biological effects such as anti-tumor, anti-inflammatory, immunomodulating, antioxidant and antimicrobial [1,2]. It exerted antiviral activities against diverse viruses, such as dengue [3], hepatitis B [4], Zika and chikungunya viruses [5].

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References

  1. Moghadamtousi SZ., et al. “A review on antibacterial, antiviral, and antifungal activity of curcumin”. Biomed Research International 2014 (2014): 186864.
  2. Praditya D., et al. “Anti-infective properties of the golden spice curcumin”. Frontiers in Microbiology 10 (2019): 912.
  3. Balasubramanian A., et al. “Inhibition of dengue virus by curcuminoids”. Antiviral Research 162 (2019): 71-78.
  4. Hesari A., et al. “Effects of curcumin on NF-κB, AP-1, and Wnt/βcatenin signaling pathway in hepatitis B virus infection”. Journal of Cellular Biochemistry 119 (2018): 7898-7904.
  5. Mounce BC., et al. “Curcumin inhibits Zika and Chikungunya virus infection by inhibiting cell binding”. Antiviral Research 142 (2017): 148-157.
  6. Zahedipour F., et al. “Potential effects of curcumin in the treatment of COVID-19 infection”. Phytotherapy Research 19 (2020): 10.1002.
  7. Tsuda T. “Curcumin as a functional food-derived factor: degradation products, metabolites, bioactivity, and future perspectives”. Food Function2 (2018): 705-714.
  8. Oso BJ., et al. “Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases”. Journal of Biomolecular Structure and Dynamics (2020): 1-12.
  9. Liu Z and Ying Y. “The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia”. Frontiers in Cell and Developmental Biology 8 (2020): 479.
  10. Anand P., et al. “Bioavailability of curcumin: problems and promises”. Molecular Pharmaceutics6 (2007): 807-818.
  11. Jäger R., et al. “Comparative absorption of curcumin formulations”. Nutritional Journal 13 (2014): 11.
  12. Moballegh Nasery M., et al. “Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review”. Molecules3 (2020): 689.
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Citation

Citation: Ahmed M Abd-Alkhalek and Omayma A Eldahshan. “Managements of COVID-19 by Curcumin". Acta Scientific Pharmaceutical Sciences 5.1 (2021): 95-96.




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Acceptance rate32%
Acceptance to publication20-30 days
Impact Factor0.759

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