Curcumin, the polyphenolic compound in turmeric exhibited versatile biological effects such as anti-tumor, anti-inflammatory, immunomodulating, antioxidant and antimicrobial [1,2]. It exerted antiviral activities against diverse viruses, such as dengue [3], hepatitis B [4], Zika and chikungunya viruses [5].

References

1. Moghadamtousi SZ., et al. “A review on antibacterial, antiviral, and antifungal activity of curcumin”. Biomed Research International 2014 (2014): 186864.
2. Praditya D., et al. “Anti-infective properties of the golden spice curcumin”. Frontiers in Microbiology 10 (2019): 912.
3. Balasubramanian A., et al. “Inhibition of dengue virus by curcuminoids”. Antiviral Research 162 (2019): 71-78.
4. Hesari A., et al. “Effects of curcumin on NF-κB, AP-1, and Wnt/βcatenin signaling pathway in hepatitis B virus infection”. Journal of Cellular Biochemistry 119 (2018): 7898-7904.
5. Mounce BC., et al. “Curcumin inhibits Zika and Chikungunya virus infection by inhibiting cell binding”. Antiviral Research 142 (2017): 148-157.
6. Zahedipour F., et al. “Potential effects of curcumin in the treatment of COVID-19 infection”. Phytotherapy Research 19 (2020): 10.1002.
7. Tsuda T. “Curcumin as a functional food-derived factor: degradation products, metabolites, bioactivity, and future perspectives”. Food Function2 (2018): 705-714.
8. Oso BJ., et al. “Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases”. Journal of Biomolecular Structure and Dynamics (2020): 1-12.
9. Liu Z and Ying Y. “The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia”. Frontiers in Cell and Developmental Biology 8 (2020): 479.
10. Anand P., et al. “Bioavailability of curcumin: problems and promises”. Molecular Pharmaceutics6 (2007): 807-818.
11. Jäger R., et al. “Comparative absorption of curcumin formulations”. Nutritional Journal 13 (2014): 11.
12. Moballegh Nasery M., et al. “Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review”. Molecules3 (2020): 689.

Citation

Citation: Ahmed M Abd-Alkhalek and Omayma A Eldahshan. “Managements of COVID-19 by Curcumin". Acta Scientific Pharmaceutical Sciences 5.1 (2021): 95-96.

Copyright

Copyright: © 2021 Ahmed M Abd-Alkhalek and Omayma A Eldahshan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.