Abstract

  Innumerable natural products with inherent potential biological activity procured from plants have played a significant role in improving the human health since the dawn of civilisation. As more than 50% of modern clinical drugs originate from natural products. Therefore, based on latter, the approach to new drug discovery and its development in the pharmaceutical industry has emerged significantly. A. vasica is a good source of pyrroloquinoline alkaloids such as vasicine, vasicol, adhatodine, vasicinone, vasicinol, vasicinolone etc. which are the chief constituents of different extracts of the plant. These compounds have shown many biological and pharmacological activities viz. anti-malarial, anti-inflammatory, antioxidant, antidiabetic, anti-bacterial, anti-cancer etc. Further, Adhatoda leaves have been used extensively in Ayurvedic medicine for the treatment of diarrhea, dysentery, tuberculosis, skin diseases, vomiting and leprosy etc. Herbal medicine is still the mainstay of about 75-80% of the world population, mainly in the developing countries, for primary health care because of better cultural acceptability, better compatibility with the human body and lesser side effects. However, the last few years have seen a major increase in their use in the developed world. As far as contemporary drugs are concerned they must be further characterized after their pharmacological screening by studying the pharmacokinetic and pharmacodynamic properties, including toxicity. Therefore, the present communication enumerate the phytochemical composition and pharmacological potential of A. vasica.

Keywords: Adhatoda vasica; Secondary Metabolites; Pyrroloquinoline Alkaloids; Biological Activities

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Citation

Citation: Raaz K Maheshwari., et al. “Phytochemical Composition and Pharmacological Potential of Adhatoda zeylanica Medic. Syn. A. vasica L. Nees".Acta Scientific Pharmaceutical Sciences 4.12 (2020): 16-21.

Copyright

Copyright: © 2020 Raaz K Maheshwari., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.