Abstract

  Depression is a serious medical illness that aggravates the negative feelings of a person that causes changes in their behaviour and thinking process. It is characterised by persistently low mood and/or loss of interest in daily activities. It leads to variety of emotional and physical problems can decrease a person ability to function at work and home. The major hypothesis of depression was primarily demonstrated 30 years ago in which it is stated that the prominent symptoms of depression are caused due to the functional deficiency of the brain monoaminergic transmitter’s norepinephrine (NE), 5-HT and/or dopamine (DA). Depression affects much more than moods. There are a few most common physical symptoms of depression:

• Increased body pains, which is seen mostly in two out of three people with depression.
• Severe fatigue.
• Lack of interest in sex.
• Loss of appetite.
• Insomnia, lack of deep sleep or oversleeping.

Keywords: Depression; Norepinephrine (NE); Dopamine (DA); Mansoa alliacea

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Citation

Citation: Ooha Deepika Gummadi., et al. “Evaluation of Depressant Activity on Mansoa alliacea on Rats". Acta Scientific Pharmaceutical Sciences 4.10 (2020): 61-64.

Copyright

Copyright: © 2020 Ooha Deepika Gummadi., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.