Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 4 Issue 11

Evaluation of Depressant Activity on Mansoa alliacea on Rats

Nayudu Teja1, Ooha Deepika Gummadi1*, Bolla Valli Devi2 and Naidu Pavani2

1Department of Pharmaceutics, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India
2Department of Pharmacy, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India

*Corresponding Author: Ooha Deepika Gummadi, Department of Pharmaceutics, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India.

Received: September 03, 2020; Published: October 16, 2020



  Depression is a serious medical illness that aggravates the negative feelings of a person that causes changes in their behaviour and thinking process. It is characterised by persistently low mood and/or loss of interest in daily activities. It leads to variety of emotional and physical problems can decrease a person ability to function at work and home. The major hypothesis of depression was primarily demonstrated 30 years ago in which it is stated that the prominent symptoms of depression are caused due to the functional deficiency of the brain monoaminergic transmitter’s norepinephrine (NE), 5-HT and/or dopamine (DA). Depression affects much more than moods. There are a few most common physical symptoms of depression:

  • Increased body pains, which is seen mostly in two out of three people with depression.
  • Severe fatigue.
  • Lack of interest in sex.
  • Loss of appetite.
  • Insomnia, lack of deep sleep or oversleeping.


Keywords: Depression; Norepinephrine (NE); Dopamine (DA); Mansoa alliacea



  1. “Numbers of threatened species by major groups of organisms (1996-2010)”. International Union for Conservation of Nature (2010).
  2. Field CB., et al. “Primary Production of the biosphere: Integrating terrestrial and oceanic Components”. Science5374 (1998): 237-240.
  3. Krek M. “Enigma of the First Arabic Book Printed from Movable Type”. Journal of Near Eastern Studies3 (1979): 203-212.
  4. Britannica Online Encyclopedia (2009).
  5. Smith AL. “Oxford dictionary of biochemistry and molecular biology”. Oxford University Press (1997).
  6. Rabin Witch E and Govindjee. “Photosynthesis”. Wiley, London (1969).
  7. Ahn K. “The worldwide trend of using botanical drugs and strategies for developing global drug”. BMB Reports3 (2017): 111-116.
  8. Sandberg F and Corrigan D. “Natural Remedies”. Their Origins and Uses. Abingdon: Taylor and Francis (2001).
  9. Schulz V., et al. “Rational Phototherapy”. A Physician’s Guide to Herbal Medicine. 4th Berlin: Springer-Verlag (2001): 306.
  10. Calixto JB. “Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)”. Brazilian Journal of Medical and Biological Research 2 (2000): 179-189.
  11. Arsdall Anne V. “Medieval Herbal Remedies: The Old English Herbarium and Anglo-Saxon Medicine”. Psychology Press (2002): 70-71.
  12. Mills Frank A. “Botany”. In Johnston, William M. (edition.). Encyclopedia of Monasticism: M-Z. Taylor andamp; Francis (2000): 179.
  13. Ramos-e-Silva Marcia. “Saint Hildegard Von Bingen (1098-1179); The Light of Her People and of Her Time”. International Journal of Dermatology4 (1999): 315-320.
  14. Castleman Michael. The New Healing Herbs. Rodale (2001): 15.
  15. Singer Charles. “Herbals”. The Edinburgh Review 237 (1923): 95-112.


Citation: Ooha Deepika Gummadi., et al. “Evaluation of Depressant Activity on Mansoa alliacea on Rats". Acta Scientific Pharmaceutical Sciences 4.10 (2020): 61-64.


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