Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 4 Issue 11

Evaluation of Depressant Activity on Mansoa alliacea on Rats

Nayudu Teja1, Ooha Deepika Gummadi1*, Bolla Valli Devi2 and Naidu Pavani2

1Department of Pharmaceutics, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India
2Department of Pharmacy, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India

*Corresponding Author: Ooha Deepika Gummadi, Department of Pharmaceutics, V.V Institute of Pharmaceutical Sciences, Gudlavaleru, Andhra Pradesh, India.

Received: September 03, 2020; Published: October 16, 2020

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Abstract

  Depression is a serious medical illness that aggravates the negative feelings of a person that causes changes in their behaviour and thinking process. It is characterised by persistently low mood and/or loss of interest in daily activities. It leads to variety of emotional and physical problems can decrease a person ability to function at work and home. The major hypothesis of depression was primarily demonstrated 30 years ago in which it is stated that the prominent symptoms of depression are caused due to the functional deficiency of the brain monoaminergic transmitter’s norepinephrine (NE), 5-HT and/or dopamine (DA). Depression affects much more than moods. There are a few most common physical symptoms of depression:

  • Increased body pains, which is seen mostly in two out of three people with depression.
  • Severe fatigue.
  • Lack of interest in sex.
  • Loss of appetite.
  • Insomnia, lack of deep sleep or oversleeping.

 

Keywords: Depression; Norepinephrine (NE); Dopamine (DA); Mansoa alliacea

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Citation

Citation: Ooha Deepika Gummadi., et al. “Evaluation of Depressant Activity on Mansoa alliacea on Rats". Acta Scientific Pharmaceutical Sciences 4.10 (2020): 61-64.




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Acceptance rate32%
Acceptance to publication20-30 days
Impact Factor0.759

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