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Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Mini Review Volume 4 Issue 8

Corona Virus Impacts to Dental Practice and Potential Salivary Identification

Vibhor Dudhraj1, Debraj Mukhopadhyay1*, Srikanta Chandra2, Ananya Rakshit3, Kritika Jain4, Tathagata Roy5 and Lucky Mukherjee6

1Department of Public Health, School of Allied Health Sciences, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi, India
2Assistant Professor of Jakir Hossain Institute of Pharmacy, Miapur, Raghunathganj, Murshidabad, India
3Department of Pharmacology, Government Medical College, Bhavnagar, Gujrat, India
4Department of Public Health, International Laureate University, Sydney, Australia
5Assistant Professor of JIS University, Department of Pharmaceutical Technology, Kolkata, India
6Assistant Professor of Sister Nivedita University, Department of Pharmaceutical Technology, India

*Corresponding Author: Debraj Mukhopadhyay, Department of Public Health, School of Allied Health Sciences, Delhi Pharmaceutical Sciences and Research University (DPSRU), New Delhi, India.

Received: July 20, 2020; Published: July 30, 2020



 A novel coronavirus (COVID-19) is associated with human to human transmission. The COVID-19 was recently identified saliva of infected patients. The possibilities of transmission by the saliva of this virus are discussed in this article. The dental clinical procedures are expected to transmit COVID-19 through contact with droplets and aerosols. In order to improve efficient strategies for prevention, especially for dentists and health professionals performing aerosol generation procedures, it is essential strategies that more investigation into the detection and impact of COVID-19 in oral fluids be made – savior which can play a crucial role in human to human transmission, can be convenient and economic health care platform for quick and early detection of COVID-19 infection through non- invasive salivation diagnostics.

Keywords: Novel Coronavirus; Human Transmission; Health Professions; Dentists; Salivation



  1. The Lancet. “Emerging understandings of COVID-19”. Lancet 10221 (2020): 311.
  2. Zhu N., et al. “China Novel Coronavirus Investigating and Research Team. A novel coronavirus from pa- tients with pneumonia in China”. The New England Journal of Medicine (2020).
  3. Zhou P., et al. “A pneumonia outbreak associated with a new coronavirus of probable bat origin”. Nature 579 (2020): 270-273.
  4. Ksiazek TG., et al. “A novel coronavirus associated with severe acute respiratory syndrome”. The New England Journal of Medicine 20 (2003): 1953-1966.
  5. de Groot RJ., et al. “Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group”. Journal of Virology14 (2013): 7790-7792.
  6. Hui DSC and Zumla A. “Severe acute respiratory syndrome: historical, epidemiologic, and clinical features”. Infectious Disease Clinics of North America 4 (2013): 869-889.
  7. To KK., et al. “Consistent detection of 2019 novel coronavirus in saliva”. Clinical Infection Disease (2020).
  8. Huang C., et al. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. Lancet S0140-6736 (2020): 30183-30185.
  9. World Health Organization – WHO. Emergencies prepared- ness, response. Pneumonia of unknown origin - China disease out- break news (2020a).
  10. Wu A., et al. “Genome composition and divergence of the novel coronavirus (COVID-19) originating in China”. Cell Host Microbe S1931-3128 (2020): 30072- X.
  11. Shu Y and McCauley J. “GISAID: global initiative on sharing all influenza data - from vision to reality”. Eurosurveillance13 (2020).
  12. ECDC - European Centre for Disease Prevention and Control; European surveillance for human infection with novel coronavirus (COVID-19).
  13. World Health Organization-WHO. Global surveillance for human infection with novel coronavirus (COVID-19) Interim guidance (2020).
  14. Xie X., et al. “Exhaled droplets due to talking and coughing". Journal of the Royal Society Interface 6 (2009): S703-S714.
  15. Chan JF., et al. “A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster”. Lancet (2020).
  16. Wang D., et al. “Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China”. JAMA (2020).
  17. Group of Interventional Respiratory Medicine, Chinese Thoracic Society. “Expert consensus for bronchoscopy during the epidemic of 2019 Novel Coronavirus infection (Trial version)”. 43 (2020): E006.
  18. Barzon L., et al. “Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016”. Eurosurveillance10 (2016): 30159.
  19. Zuanazzi D., et al. “Postnatal identification of zika virus peptides from saliva”. Journal of Dentistry Research10 (2010): 1078-1084.
  20. Segal A and Wong DT. “Salivary diagnostics: enhancing disease detection and making medicine better”. European Journal of Dental Education 12 (2008): 22-29.
  21. Silva-Boghossian CM., et al. “Quantitative proteomic analysis of gingival crevicular fluid in different periodontal conditions”. PLoS One10 (2013): e75898.
  22. Liu L., et al. “Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques”. Journal of Virology8 (2011): 4025-4030.
  23. Lu B., et al. “Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice”. Immunology2 (2010): 254-261.


Citation: Debraj Mukhopadhyay., et al. “Corona Virus Impacts to Dental Practice and Potential Salivary Identification". Acta Scientific Pharmaceutical Sciences 4.8 (2020): 127-130.


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