Acta Scientific Pharmaceutical Sciences (ISSN: 2581-883X)

Editorial Volume 4 Issue 8

Loading sd-rxRNAi into Tumors: Are We Getting Close with TGF-β1 Targeting?

Ashok K Singh1* and Aakansha Singh2

1Postdoctoral Research Trainee, Pennsylvania State University, Penn State College of Medicine, Hershey, PA, USA
2Associate Research Analyst, Clarivate Analytics, Hyderabad, Telangana, India

*Corresponding Author: Ashok K Singh, Postdoctoral Research Trainee, Pennsylvania State University, Penn State College of Medicine, Hershey, PA, USA.

Received: June 20, 2020; Published: June 26, 2020

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Adoptive cell therapies (ACT) that redirect T cells to specifically target cancer using genetically engineered T cell receptor or chimeric antigen receptor T cells are emerging forms of immunotherapy. Natural killer (NK) cells serve as a crucial first line of defense against tumors and can be activated rapidly to target and kill tumor cells without prior sensitization. NK cells are winning candidates for use in ACT because matching to a specific patient is not required. Thus, making an off-the-shelf NK therapy product could be possible.

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References

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Citation

Citation: Ashok K Singh and Aakansha Singh. “Loading sd-rxRNAi into Tumors: Are We Getting Close with TGF-β1 Targeting?".Acta Scientific Pharmaceutical Sciences 4.8 (2020): 01-02.



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