Abstract

  Solar UV radiation is one of the important environmental risk factors for development of non-melanoma skin cancer. It can also cause atrophy, wrinkling, pigmentary changes, photosensitivity reactions to ingested drugs etc. Efforts are, therefore, going on to invent sources through which solar UV rays can be absorbed. Recently we have shown that ethanol extract of Ageratum conyzoides Linn (A. conyzoides L.) leaves of summer sample has maximum UV radiation absorption activity. Aim of the present work was to isolate the active compound(s) from the A. conyzoides L. leaves responsible for UV radiation absorption. A. conyzoides L. leaves were collected in summer, identified by the taxonomist and processed for isolation work to get the active compound responsible for UV radiation absorption property by standard methods. Solvent extraction and acid hydrolysis were done followed by solvent treatment, chromatographic experiments. Finally a compound was crystallized. UV absorption property of the isolated compound was studied. The compound showed maximum absorption at 200 nm. The compound, therefore, may be used to prepare sun screen lotion to protect humans from UV radiation.

Keywords: Ageratum conyzoides Linn. Leaves; UV Absorbing Property; Isolation of Active Compound; Sun Screen Lotion.

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Citation

Citation: Prasanta Kumar Mitra., et al. “Isolation of One Compound from Ageratum conyzoides L. Leaves Responsible for UV Radiation Absorption" Acta Scientific Pharmaceutical Sciences 4.2 (2020): 21-24.