Acta Scientific Pharmaceutical Sciences (ASPS)(ISSN: 2581-5423)

Research Article Volume 4 Issue 3

IEffect of Aqueous Extract of Talinum triangulare on Reproductive Parameters of Female Wistar Rats

Oshomoh EO1* and Obaro-onezeyi OE2

1Department of Science Laboratory Technology, University of Benin, Benin City, Nigeria
2Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria

*Corresponding Author: Oshomoh EO, Department of Science Laboratory Technology, University of Benin, Benin City, Nigeria.

Received: January 27, 2020; Published: February 08, 2020

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Abstract

  Talinum triangulare commonly called water leaf, grows under humid temperature up to 10-15 cm in height, germinate in five days after planting with rapid growth pattern in presence of sufficient water and in 3 weeks becomes ready for harvest and consumption. There was positive effect of T. triangulare on the reproductive parameter of matured female Wister rats. Twelve groups of rats (5 each) were orally administered the extracts at three doses; 0, 30, 120 and 700 mg/kg/wt./ day for a period of 21 and 28 days. Body mass and vaginal smear were collected and recorded every seven days and every day except the pregnant Dams in the pregnancy outcome study groups had virginal smear collection discontinued when sperm was present in the virginal which was day zero of pregnancy, only animals on pro-estrus phase were either anesthetized or mated. Pregnancy outcome parameters such as leitter size, eye opening day, fur appearing day, were examined in pregnancy outcome study, other reproductive parameters such as leuthenizing hormones (LH), follicle stimulating hormones (FSH) and Estrogen-2 (E-2) hormones were observed. The findings revealed a significant increase in body mass in all groups administered with the extract when compared to the control, the extract groups were seen to have significant increase in weight of reproductive organs. Hormonal assays showed observable elevation of hormonal levels at the estrus phase on the following parameter: LH, E-2 and FSH. Hematological indices of dams were done using standard procedures. The study showed that the plant extract was safe at 30, 120 and 700 mg/kg. Therefore, T. triangulare leaves improved reproductive parameters and efficient in the management of pregnancy, infertility and as blood builder in children and adult.

Keywords: Pregnancy; Infertility; Oestrous Cycle; Inhibins; Leitter Size

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Citation

Citation: Oshomoh EO and Obaro-onezeyi OE. “Effect of Aqueous Extract of Talinum triangulare on Reproductive Parameters of Female Wistar Rats". Acta Scientific Pharmaceutical Sciences 4.3 (2020): 01-09.



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