Abstract

  Talinum triangulare commonly called water leaf, grows under humid temperature up to 10-15 cm in height, germinate in five days after planting with rapid growth pattern in presence of sufficient water and in 3 weeks becomes ready for harvest and consumption. There was positive effect of T. triangulare on the reproductive parameter of matured female Wister rats. Twelve groups of rats (5 each) were orally administered the extracts at three doses; 0, 30, 120 and 700 mg/kg/wt./ day for a period of 21 and 28 days. Body mass and vaginal smear were collected and recorded every seven days and every day except the pregnant Dams in the pregnancy outcome study groups had virginal smear collection discontinued when sperm was present in the virginal which was day zero of pregnancy, only animals on pro-estrus phase were either anesthetized or mated. Pregnancy outcome parameters such as leitter size, eye opening day, fur appearing day, were examined in pregnancy outcome study, other reproductive parameters such as leuthenizing hormones (LH), follicle stimulating hormones (FSH) and Estrogen-2 (E-2) hormones were observed. The findings revealed a significant increase in body mass in all groups administered with the extract when compared to the control, the extract groups were seen to have significant increase in weight of reproductive organs. Hormonal assays showed observable elevation of hormonal levels at the estrus phase on the following parameter: LH, E-2 and FSH. Hematological indices of dams were done using standard procedures. The study showed that the plant extract was safe at 30, 120 and 700 mg/kg. Therefore, T. triangulare leaves improved reproductive parameters and efficient in the management of pregnancy, infertility and as blood builder in children and adult.

Keywords: Pregnancy; Infertility; Oestrous Cycle; Inhibins; Leitter Size

References

1. Edema AO. “Product of some common vegetable”. Journal of Nutrition 6 (2010): 1-5.
2. Oyewole OI and Akingbala OA. “Phytochemical analysis and hypolipidemic properties of Jathropher tanjorensis leaf extract”. European journal 1.14 (2011): 180-185.
3. Ezekwe MO., et al. “Beneficial influence of purslane and water leaf supplement to humans”. Nigerian food Journal 16 (2010): 39.
4. Schippers RR. “African indigenous vegetables: An overview of the cultivated species”. Chatham, United Kingdom. (2009): 214.
5. Lyndrup J and Lamont RF. “The choice of a tocolytic for the treatment of preterm labor: a clinical Evaluation of Nifedipine Versus Atosiban Expert opinion investigation”. Drugs 16.6 (2007): 843- 853.
6. Jungwirt A., et al. “Guide Lines on male fertility”. European Association Urology 15 (2015): 1-42.
7. Reid CD., et al. “Endogenous erythroid clones (EEC) in polychaemiaand their their relationship to diagnosis and the response to treatment”. Brazilian Journal of Haematology (1988): 395-400. 
8. Soetan KO., et al. “Preliminary studies on haematological parameter of cockerels fed raw and processed guinea corn (sorghum bicolor)”. Proceedings of 38^th Annual Conference of Nigeria Society for Animal Production 2013: 49-52.
9. Sadeghi BM., et al. “The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model”. Bone Marrow Transplant 41 (2008): 895-904.
10. Nasibeh R., et al. “Factors associated with preterm labor in Hormozgan Province in 2013”. Electronic Physician 8.8 (2016): 2918-2923.
11. Adaay MH., et al. “Effect of Aqueous Extract of Medical- sativa officinalis Mixture on Hormonal, Ovarian and Uterine parameter in female mice”. Journal of material and environmental science 4.4 (2013): 424-433.
12. Pierre W., et al. “Albert animal physiology, Department of Animal Biology of Dschang University, Cameroon, Department of Chemistry Box67 Cameroon”. Journal of African Health Science 9 (2009): 225-231.
13. Clarissa LH., et al. “Effects of two Phytotherapic Formulations Containing Glycine Max (L.) Merr on Male Rat Fertility”. 34.1 (2012): 31-39.
14. Ojeme V. “Infertility in Nigeria at 60% - Gynecologist’’. Vanguard Media limited; Nigeria (2016).
15. Jones EE and DeCherney AH. “The female reproductive system”. In: Boron, W. F., Boulpaep, E. L. (Eds.). Medical physiology. A cellular and molecular approach. Elsevier Saunder, USA. (2005): 1141-1165.
16. Mascarenhas MN., et al. “National, Regional and Global trends in infertility prevalence since 1990: A systematic Analysis of 277 Health surveys”. PLOS Medicine 9.12 (2016): e1001356.
17. Chima UD., et al. “A Survey of plants used in the treatment of ante-Natal and post Natal Disorder in Nneoch local Government Area of Abia state Nigeria Their Knowledge and uses by Traditional Healers”. Greener Journal of Biological Sciences 3.6 (2013): 229-237.
18. Sani HD and Aliyu BS. “A survey or Major Ethnic Medicinal Plants of kano Northern Nigeria, Their knowledge and uses by traditional healers”. Bayero Journal of Pure Applied Science 4 (2011): 28-34.
19. Monalil G., et al. ‘Traditional Methods of reproductive Healthcare practises and fertility control among the Bhumija tribes of Baleswar, Orissa”. Ethnomedicine 5 (2011): 51-55.
20. Bafor EE., et al. “In vitro determination of the uterine stimulatory effect of the aqueous extract of Ficus exaspirata”. Journal of Ethnopharmacology 127.2 (2010): 502-507.
21. Abasi N., et al. “Hematological parameter and factor affecting their values”. Journal of Agricultural Science 2.1 (2015): 37-47.
22. Al-Snafi AE. “The Chemical Constituents and Pharmacological Effect of Capsella busar-pastery”. A Review Scholars Academic Journal of Pharmacy 5.5 (2016): 159-174.
23. Obaro-onezeyi OE and Oshomoh EO. “Assessment of several concentrations of aqueous extract of Croton lobactus (Linn) on reproductive parameters of Wistar Rats”. Journal of Science and Technology Research 1.1 (2019): 72-80.

Citation

Citation: Oshomoh EO and Obaro-onezeyi OE. “Effect of Aqueous Extract of Talinum triangulare on Reproductive Parameters of Female Wistar Rats". Acta Scientific Pharmaceutical Sciences 4.3 (2020): 01-09.