KG Bhutkar1*, AR Sakore2, Ruchi Kumari1, Khusboo Kachariya1
1Department of Pharmacognosy, GSMCOP Wagholi, Pune, Maharashtra, India
2Department of Pharmaceutical Chemistry, GSMCOP Wagholi, Pune, Maharashtra, India
*Corresponding Author: KG Bhutkar, Department of Pharmacognosy, GSMCOP Wagholi, Pune, Maharashtra, India.
Received: March 05, 2018; Published: May 18, 2018
Citation: KG Bhutkar., et al. “Phytochemical Aspects and Development of Herbal Cookies for Treatment of Obesity”. Acta Scientific Pharmaceutical Sciences 2.6 (2018).
Obesity is a Multifactorial disorder of energy balance. It is characterized by an excessive Body Mass Index. If BMI is > 30 kg/m2, it is called as obesity. Obesity leads to many multi disorders like- types-II diabetes, heart diseases, gout, sleep apnea, osteoarthritis, obesity hypoventilation syndrome etc. Obesity takes place due to lipids which are essential for healthy cell functions as long as they are not in excess amount in our body. There are three types of lipids: LDL (below 100 is optimum) HDL (above 60 it gives protection against heart diseases) and Triglycerides are stored as fats (above 150 it increases the rate of heart attack and stroke). Ant obesity drugs available in markets are such as Orlistat, Sibutramine, Amphetamine having side effects like abdominal cramp, GIT disorders, dry mouth, tachycardia, constipation, insomnia etc. So, to overcome these side effects herbal drugs are introduced as it is the oldest and most widely used system of medicine in the world today as they have less side effects and are easily available. We had formulated herbal cookies which are administered orally and degraded in stomach and it breaks the anabolism of lipid via β-Oxidation which is responsible for deposition of cholesterol in the body. The specialty of our formulation is that it increases lipolysis and energy expen- diture which maintains the body weight and decreases fat absorption by preventing breakdown of dietary fat in GIT.
Keywords: High Density Lipoproteins; Multifactorial; Lipolysis; Low Density Lipoproteins; Triglycerides
Copyright: © 2018 KG Bhutkar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.