Acta Scientific Pharmaceutical Sciences

Research ArticleVolume 1 Issue 5

Antibacterial Activity and Phytochemical Analysis of Leaf Extracts of Calotropis procera

Hilal-Ul-Zaman* and Shakeel Ahmad

Govt. M.V.M College, Bhopal, India

*Corresponding Author: Hilal-Ul-Zaman, Govt. M.V.M College, Bhopal, India.

Received: September 08, 2017; Published: October 24, 2017

Citation: Hilal-Ul-Zaman and Shakeel Ahmad. “Antibacterial Activity and Phytochemical Analysis of Leaf Extracts of Calotropis procera”. Acta Scientific Pharmaceutical Sciences 1.5 (2018).

Abstract

  Phytochemical and antibacterial activities of petroleum ether, chloroform and ethanolic extract obtained from the leaves of Calotropis procera were investigated in an attempt to evaluate its medicinal potentials. The phytochemical screening revealed the presence alkaloids, saponins, tannins, flavonoids, amino acids and other phenolic compounds with a very high content in ethanolic extracts. The concentration of the phytochemical constituents were in the order of ethanol > chloroform > petroleum ether. Antibacterial activity was determined against E. coli, S. aureus, P. aeruginosa, K. pneumoniae was carried in well diffusion method. The zone of inhibition produced by the crude extracts of petroleum ether, chloroform and ethanol extracts against sensitive bacteria. The results obtained showed that petroleum ether, chloroform and ethanol extracts of Calotropis procera Linn, had inhibitory effect on the growth of isolates. The effect exhibited by ethanolic extract of leaves was significantly greater than the other two. The obtained results provide a support for the use of Calotropis procera Linn, in traditional medicine and suggest its further advance investigation.

Keywords: Antibacterial Activity; Phytochemical Analysis; Calotropis procera

Copyright: © 2018 Hilal-Ul-Zaman and Shakeel Ahmad. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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