Mir Mohammad Yusuf¹*, Farhana Ahmed² and M Monir Hussain³

¹ Associate Professor, Critical Care Department of Pediatrics, Bangladesh Shishu Hospital and Institute, Bangladesh
²Assistant Professor, Department of Pediatric Neuroscience, Bangladesh Shishu Hospital and Institute, Bangladesh
³Professor, Department of Neonatology, Bangladesh Shishu Hospital and Institute, Bangladesh

*Corresponding Author: Mir Mohammad Yusuf, Associate Professor, Critical Care Department of Pediatrics, Bangladesh Shishu Hospital and Institute, Bangladesh.

Received: April 29, 2025; Published: May 18, 2025

Abstract

Objectives: Neonatal mortality rate is one of the key indicator in the health status of a nation, and directly reflects prenatal, intra partum, and neonatal care.

Aim of this study: To find out the association of electrolyte and acid base disorder in critically sick neonates at the time of admission in NICU as predictor of their mortality.

Methods: This retrospective study was conducted in the department of Neonatology, Bangladesh Shishu Hospital and Institute (BSH&I), Sher-E-Bangla Nagar, Dhaka, from January 2023 to June 2023. Total 115 neonates were included in this study having serum electrolyte and arterial blood gas with other basic biochemical parameter analyzed at the time of admission.

Results: Blood pH, HCO3-, Base excess were lower, Sodium (Na+) level and anion gap were higher in non-survivors than survivors group which were statistical significant (p < 0.05). No statistical significant different regarding PCO2, PO2, potassium (K+) and chlo ride level (p > 0.05). Multivariable logistic regression analysis identified a higher AG (OR 1.321, 95% CI 1.14-1.53; p < 0.001) at the time of admission in NICU as predictor of mortality.

Conclusion: A higher AG (anion gap) at the time of admission in NICU identified as strongest predictor of mortality.

Keywords: NICU; Electrolyte and Acid-Base Disorder; Mortality Predictor

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Citation

Citation: Mir Mohammad Yusuf., et al. “Role of Electrolyte and Acid-Base Disorder of Critically Sick Neonates at the Time of Admission in a Tertiary NICU as Predictor of their Mortality: A Retrospective Study".Acta Scientific Paediatrics 8.6 (2025): 01-06.

Copyright

Copyright: © 2025 Mir Mohammad Yusuf., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.