Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 8 Issue 3

Takayasu's Arteritis Complicated with Myocardial Infarction in an Elderly Patient: A Rare Case Report

Marina Kuparadze1,2, Natalia Garuchava1, Gigi Gorgadze1*, Nika Ichkiti1 and Giorgi Zhorzholiani1

1 Tbilisi State Medical University, Georgia
2Cardiology Clinic “Guli”, Georgia

*Corresponding Author: Gigi Gorgadze, Tbilisi State Medical University, Georgia.

Received: March 10, 2025; Published: March 24, 2025

Abstract

Takayasu’s arteritis (TA) is a condition similar to other forms of vasculitis, such as giant cell arteritis, which predominantly occurs in older adults. TA may present as a pulseless disease. This article describes a clinical case of TA in an 80-year-old woman who has been under observation since 2020.
The patient came to the clinic with the following complaints: chest pain behind the sternum radiating to the left shoulder, dry cough, shortness of breath, and mild ataxia. Echocardiography was performed, which showed moderate dilatation of the left ven tricle, calcification of the aortic annulus and mitral valve semilunar cusps, and moderate hypertrophy of the left ventricle. Additional studies were prescribed. Dopplerography showed left ventricular diastolic dysfunction, aortic and mitral valve regur gitation, and cor pulmonale with pulmonary hypertension. On the X-ray, the bronchovascular pattern of the lungs was enhanced, the right sinus was not illuminated, and the left was free. On the ECG, depression of the T and ST segments was pronounced without acute damage. As a result of ultrasonographic and angiological examinations, a diagnosis of TA was made, complicated by a myocardial infarction.
Appropriate treatment with methotrexate was performed, accompanied by corticosteroids, namely prednisolone.
In order to prevent complications, monitoring has been carried out for four years. At this stage, the disease is not progressing. No additional complications have occurred. This clinical case is interesting both in terms of the course of the disease and its manage ment

Keywords: Takayasu’s Arteritis (TA); Myocardial Infarction (MI)

References

  1. Sano M. “Complexity of Inflammation in the. Trajectory of Vascular Disease: Interleukin 6 and Beyond”. Annals of Vascular Diseases 25 (2023): 8-16.
  2. Szydełko-Paśko U., et al. “Ocular Manifestations of Takayasu's Arteritis-A Case-Based Systematic Review and Meta-Analysis”. Journal of Clinical Medicine11 (2023): 37-45.
  3. Danda D., et al. “Advances in Takayasu arteritis: An Asia Pacific perspective”. Frontiers in Medicine (Lausanne) (2022): 952-972.
  4. Shikino K., et al. “FDG-PET of Takayasu's arteritis”. Journal of General Internal Medicine 29 (2014): 1072-1073.
  5. Esatoglu SN and Hatemi G. “Takayasu arteritis”. Current Opinion on Rheumatology 1 (2022): 18-24.
  6. Abou Sherif S., et al. “Coronary Artery Aneurysms: A Review of the Epidemiology, Pathophysiology, Diagnosis, and Treatment”. Frontiers in Cardiovascular Medicine 5 (2017): 24.
  7. Tamura N., et al. “Single-nucleotide polymorphism of the MLX gene is associated With Takayasu arteritis”. Circulation: Genomic and Precision Medicine 11 (2018): 002296.
  8. Tezuka D., et al. “Role of FDG PET-CT in Takayasu arteritis: sensitive detection of recurrences”. JACC Cardiovascular Imaging 5 (2012): 422-429.
  9. Sugiyama K., et al. “Takayasu disease on the centenary of its discovery”. Japanese Journal of Ophthalmology 53 (2009): 81-91.
  10. Singh A., et al. “Efficacy and safety of tocilizumab in treating Takayasu arteritis: A systematic review of randomized controlled trials”. Modern Rheumatology 31 (2020): 1-20.
  11. Somashekar A and Leung YT. “Updates in the diagnosis and management of Takayasu's arteritis”. Postgraduate Medicine 135 (2023): 14-21.
  12. As C and Danda D. “Current Diagnosis and Management of Takayasu Arteritis”. International Heart Journal 64 (2023): 519-534.

Citation

Citation: Gigi Gorgadze., et al. “Takayasu's Arteritis Complicated with Myocardial Infarction in an Elderly Patient: A Rare Case Report". Acta Scientific Paediatrics 8.3 (2025): 28-35.

Copyright

Copyright: © 2025 Gigi Gorgadze., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor1.197

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Last Date to Submit Articles
    Journal accepting all the types of Articles for upcoing issue by on/before July 30, 2025
  • Issue of Publication Certificate
    Publication Certificate will be issued to the author after Online publication of an Article
  • Best Article
    One Article will be selected as Best Article from all the Articles of the corresponding Issue, once the issue released, and honored with A Best Article Certificate

Contact US









ff

© 2024 Acta Scientific, All rights reserved.