Edwin Dias¹* and Rohan Shetty²

¹Professor and HOD, Department of Paediatrics, Srinivas Institute of Medical Sciences and Research Centre, Mangalore, Karnataka State, India
²Final Year Pharm D., Srinivas College of Pharmacy, Valachil, Mangalore, Karnataka State, India

*Corresponding Author: Shamsun Nahar Shanta, Medical Officer, Department of Pediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Received: March 15, 2023; Published: November 28, 2023

Abstract

HIV is a very dangerous infection brought on by a virus whose genome is made up of two identical single-stranded RNA molecules that are encased inside the core of the virus particle. The HIV virus is the cause of paediatric AIDS. It works by suppressing the immune system, which is clinically shown as a drop in CD4 cells. Rapid CD4 cell loss and accelerated disease progression are linked to high plasma viremia in HIV-1 infection [1]. The need to begin a successful ART in children with HIV infection is all the more important given that these children have high viral loads.
Especially in early childhood. The treatment of HIV in a result of advancements in antiretroviral therapy (ART). The goal of this review paper is to give a thorough summary of the current approach es and difficulties in managing HIV infection in paediatric patients. The treatment of HIV infection in paediatric patients has dramatically changed over time thanks to developments in antiretroviral therapy (ART). This review article seeks to give readers a thorough picture of the current approaches and difficulties in managing HIV infection in paediatric patients. We discuss various aspects, including diagnosis, treatment initiation, drug selection, monitoring, adherence support, prevention of opportunistic infections, and psychosocial considerations. Additionally, we highlight the recent advancements in paediatric HIV research and the `potential future directions in managing this complex disease.

Keywords: HIV Infection; Paediatric Patients; Antiretroviral Therapy; Diagnosis; Drug Selection; Monitoring; Adherence Support; Opportunistic Infections; Psychosocial Considerations; Recent Advances; Future Directions

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Citation

Citation: Edwin Dias and Rohan Shetty. “Management Strategies for HIV Infection in Paediatric Patients: A Comprehensive Review".Acta Scientific Paediatrics 7.1 (2024): 02-13.

Copyright

Copyright: © 2024 Edwin Dias and Rohan Shetty. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.