Food Protein-Induced Proctocolitis: A Unique Subtype of Gastrointestinal
Non-IgE-mediated Food Allergy
Nilton Carlos Machado* and Mary de Assis Carvalho
Pediatric Gastroenterology, Hepatology and Nutrition Division, Department of Pediatrics, Botucatu Medical School - São Paulo State University, Botucatu, Sao Paulo, Brazil
*Corresponding Author: Nilton Carlos Machado, Associate Professor of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Botucatu Medical School – UNESP, Botucatu, São Paulo, Brazil.
Received: October 30, 2023; Published: November 01, 2023
Abstract
Food allergy (FA) is an abnormal clinical reaction to proteins in which immunologically mediated mechanisms are implicated [1]. Certainly, FA is a major global health problem, and its geographic distribution may be linked to genetic, environmental, lifestyle, and dietary factors [2]. Pediatricians are the first specialists to be sought out by family members of children suspected of having FA. Therefore, they must be trained in the principles of diagnosis and carry out appropriate referrals when necessary [3-5]. Although more than 160 foods can cause allergic reactions, eight are considered significant allergens (cow's milk, soy, egg, wheat, fish and shellfish, peanuts, and tree nuts).
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