Acta Scientific PAEDIATRICS (ISSN: 2581-883X)

Case Report Volume 6 Issue 3

Radiological Imaging Features of Wilson’s Disease in an Early Adolescent Male: Case Report

Chiraz Regaieg1,3*, Ben thabet Afef1,3, Kolsi Nadia1,3, Amira Trigui2,3, Bouraoui Amira1,3, BEN HAMED Amel1,3, Manel Charfi1,3 and Hmida Nedia1,3

1Department of Neonatology, Hedi Chaker University Hospital, University of Sfax, Sfax, Tunisia
2Department of Ophtalmology, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia
3University of Medicine of Sfax, Sfax, Tunisia

*Corresponding Author: Chiraz Regaieg, Department of Neonatology, Hedi Chaker University Hospital, University of Sfax, Sfax, Tunisia.

Received: January 20, 2023; Published: February 12, 2023

Abstract

Background: Retinopathy of prematurity (ROP) is the leading avoidable cause of childhood blindness. It is an abnormal retinal vascular development in preterm, due to several risks’ factors.

Objectives: To evaluate the results of the screening program for ROP in the neonatal care unit of Sfax.

Methods: A retrospective study of all cases of ROP screened in the neonatal intensive care unit of Sfax (Tunisia) between January 2005 and December 2020. The screening program included all preterm under 32 weeks of gestation (GW) and/or having a birth weigh less than 1500 grams and all preterm under 34 GW with one of ROP risk factors.

Results: During the study period, 3644 newborns were examined for ROP at the age of 30 days (with an average of 243 exams/year). Twelve cases of ROP were diagnosed which 5 in 2005. The incidence was 0,22% of newborns at risk. The ROP was Stage V in 5 cases, Stage III in 3 cases, Stage II in 2 cases and Stage I in 2 cases. One of the stages III ROP cases progressed to a stage IV and another to a stage V due to a delay in treatment. The mean term was 30 weeks + 3 days [26-33 GW]. The mean weight was 1425 grams [970-2050 gr]. All newborns were hospitalized for neonatal respiratory distress syndrome. Seven required mechanical ventilation which was associated to exogenous surfactant administration in 6 cases. The mean duration of oxygen therapy was 12 days [2-57 days]. Severe sepsis associated to hemodynamic disorders were observed in 7 patients. The treatment was surgical in stage IV ROP. It was based on cryotherapy in stage III and stage II ROP. Stage I ROP was treated successfully by argon laser photocoagulation. For stage V ROP cases no treatment was proposed given the definitive vision loss.

Conclusion: The incidence of ROP in our unit decreased since the renovation of the department in 2006, with the generalization of cardiorespiratory monitoring and the acquisition of a blood gas measuring device allowing the measurement and control of oxygen therapy. Furthermore, the screening enables an early diagnosis and management, which improve the prognosis. Screening can be improved by using new technologies especially the Ret-cam.

Keywords: Screening; Retinopathy; Premature; Risk Factors

References

  1. Holmström G., et al. “Increased frequency of retinopathy of prematurity over the last decade and significant regional differences”. Acta Ophthalmology2 (2018): 142-148.
  2. Kermovant-Duchemin E., et al. “Epidémiologie et physiopathologie de la rétinopathie du prématuré”. Archives de Pédiatrie 18 (2011): S79-S85.
  3. Costeloe K., et al. “The EPICure study: outcomes to discharge from hospital for infants born at the threshold of viability”. Pediatrics 106 (2000): 659-671.
  4. Lad EM., et al. “Incidence of retinopathy of prematurity in the United States: 1997 through 2005”. American Journal of Ophthalmology 148 (2009): 451-458.
  5. Good WV., et al. “The incidence and course of retinopathy of prematurity: findings from the early treatment for retinopathy of prematurity study”. Pediatrics 116 (2005): 15-23.
  6. Alpay A and Ugurbas SH. “Incidence and risk factors for retinopathy of prematurity in the West Black Sea region, turkey”. The Turkish Journal of Pediatrics (2010): 113-118.
  7. Beby F., et al. “Rétinopathie du premature: resultants de l’examen du fond de l’œil chez 94 enfants à risque”. Journal Français d'Ophtalmologie 27 (2004): 337-344.
  8. Gilbert C., et al. “Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate and high levels of development: implications for screening programs”. Pediatrics 115 (2005): e518-525.
  9. Elizabeth Hartnett M and John S. “Mechanisms and Management of retinopathy of prematurity”. The New England Journal of Medicine 367 (2012): 26.
  10. Section on ophthalmology, American Academy of Pediatrics, American Academy of Ophtalmology, American Association for Pediatric ophthalmology and strabismus. “Screening examination of premature infants for retinopathy of prematurity”. Pediatrics 117 (2006): 572-576.
  11. Wilkinson AR., et al. “UK retinopathy of prematurity guideline”. Early Human Development 84 (2008): 71-74.

Citation

Citation: Chiraz Regaieg., et al. “Retinopathy of Prematurity: Findings After 15 Years of Screening in a Neonatal Care Unit in Tunisia". Acta Scientific Paediatrics 6.3 (2023): 16-20.

Copyright

Copyright: © 2023 Chiraz Regaieg., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor1.197

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US