Shafi Ahmed¹*, Swapan Kumar Chowdhury², Palash Chandra Banik³, MH Faruquee⁴ and AFM Salim⁵*

¹Associate Professor, Department of Pediatrics, Monno Medical College and Hospital, Manikganj, Bangladesh
²PhD Fellow, Bangladesh University of Professionals, Dhaka, Bangladesh
³Assistant Professor, Department of Non-Communicable Diseases, Bangladesh
University of Health Sciences, Dhaka, Bangladesh
⁴Associate Professor, Department of Occupational and Environmental Health, Bangladesh University of Health Sciences, Dhaka, Bangladesh
⁵Ex-Professor, Institute of Child Health and Shishu Swasthya Foundation Hospital, Mirpur, Dhaka, Bangladesh

*Corresponding Author: Shafi Ahmed, Associate Professor, Department of Pediatrics, Monno Medical College and Hospital, Manikganj, Bangladesh.

Received: September 22, 2022; Published: October 17, 2022

Abstract

Vitamin D deficiency or insufficiency among the children have been widely observed by different researches. There is evidence of a relationship in human bodies between Vitamin D, Alkaline Phosphatase, Calcium, and Phosphate. A community based cross sectional study conducted among 274 primary school children of 5-14 years age group complaining growing pain during March 2018 to February 2019 to determine the relationship of vitamin D with calcium, phosphorus and alkaline phosphate among the children with growing pain. As required, 3 ml of venous blood samples were collected from the study subjects with every precaution by experienced phlebotomists after obtaining written consent from the care givers and transported to the laboratory. Sample serum were tested by the Enzyme-Linked Immunosorbent Assay (ELISA). The collected data was analyzed with Windows SPSS. The chi-square test and binary logistic regression were performed to find out the relationship among vitamin D, Alkaline Phosphatase, calcium and phosphate. Among the subjects, 85.8% were found suffering from growing pain, among them 50.2% were male and 74.0% were within the age group of 10 years (8.82 ± 2.058 years). Prevalence of growing pain was more among the subject with Vitamin D, Alkaline Phosphatase and phosphate deficiency. less than 4.5mg/dl. No statistically correlation of Vitamin D with calcium and phosphate but negative correlation with Alkaline Phosphatase were observed among the subjects with growing pain. Wide range biochemical study among the children with growing pain is highly recommended to establish the findings of the current study for appropriate management regime.

Keywords: Growing Pain; Serum Vitamin D; Alkaline Phosphatase; Calcium and Phosphate

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Citation

Citation: Shafi Ahmed., et al. “Serum Vitamin D, ALK Phosphatase, Calcium and Phosphate in Children Suffering from Growing Pain in Bangladesh". Acta Scientific Paediatrics 5.11 (2022): 17-21.

Copyright

Copyright: © 2022 Shafi Ahmed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.