Molecular Mechanisms, Clinical Approach to Diagnosis and Competent Care of Craniosynostosis
Department of Fetal Medicine and Medical Genetics, Fernandez Foundation, India
*Corresponding Author: Gayatri Nerakh, Department of Fetal Medicine and Medical Genetics, Fernandez Foundation, India.
August 04, 2022; Published: September 29, 2022
Craniosynostosis is defined as a partial or complete premature fusion of one or multiple cranial sutures resulting in distortion of skull shape and craniofacial dysmorphism. It is a heterogeneous condition with non-genetic and genetic etiology. The prevalence of craniosynostosis is 1 in 2000 and 1 in 2500 live births and is the second most common craniofacial anomaly after cleft lip/palate. Understanding the pathogenesis of craniosynostosis is very important. Knowledge of perinatal presentation of syndromic and non-syndromic craniosynostosis helps in appropriate genetic evaluation. Neurological abnormalities can be prevented/improved by early diagnosis and treatment for those who require surgical intervention.
Keywords: Clinical Approach; Craniosynostosis; Syndromes
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