Acta Scientific PAEDIATRICS (ISSN: 2581-883X)

Review Article Volume 5 Issue 10

Molecular Mechanisms, Clinical Approach to Diagnosis and Competent Care of Craniosynostosis

Gayatri Nerakh*

Department of Fetal Medicine and Medical Genetics, Fernandez Foundation, India

*Corresponding Author: Gayatri Nerakh, Department of Fetal Medicine and Medical Genetics, Fernandez Foundation, India.

Received: August 04, 2022; Published: September 29, 2022


Craniosynostosis is defined as a partial or complete premature fusion of one or multiple cranial sutures resulting in distortion of skull shape and craniofacial dysmorphism. It is a heterogeneous condition with non-genetic and genetic etiology. The prevalence of craniosynostosis is 1 in 2000 and 1 in 2500 live births and is the second most common craniofacial anomaly after cleft lip/palate. Understanding the pathogenesis of craniosynostosis is very important. Knowledge of perinatal presentation of syndromic and non-syndromic craniosynostosis helps in appropriate genetic evaluation. Neurological abnormalities can be prevented/improved by early diagnosis and treatment for those who require surgical intervention.

Keywords: Clinical Approach; Craniosynostosis; Syndromes


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Citation: Gayatri Nerakh. “Molecular Mechanisms, Clinical Approach to Diagnosis and Competent Care of Craniosynostosis". Acta Scientific Paediatrics 5.10 (2022): 19-26.


Copyright: © 2022 Gayatri Nerakh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Acceptance rate33%
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