Acta Scientific PAEDIATRICS (ISSN: 2581-883X)

Case Report Volume 5 Issue 9

Venous Thrombosis as A Complication of Primary Nephrotic Syndrome

Ceballos Gabriela E*, Plos Carlos, Rodríguez, Margaret Bell, Añasco Daiana and Liern Michael

Children's Nephrology Service, Ricardo Gutiérrez Children's General Hospital, Buenos Aires, Argentina

*Corresponding Author: Ceballos Gabriela E, Children's Nephrology Service, Ricardo Gutiérrez Children's General Hospital, Buenos Aires, Argentina.

Received: June 24, 2022; Published: August 25, 2022

Abstract

Introduction: Children suffering from nephrotic syndrome have an increased risk of arterial and venous thrombosis, depending on their location and extent, they can be life-threatening.

Objective: To describe a clinical case of complicated nephrotic syndrome with venous thrombosis.

Description: 5-year-old boy diagnosed with minimal nephrotic syndrome diagnosed by renal biopsy presenting at 10 days consulta for pain and erythema on the right side of the neck of 24 hours of evolution. Diagnosis: deep vein thrombosis in confluent yugulo right subclavian. It was performed or inter consultation with hematology and initiation or anticoagulation. At the 3rd month of the anticoagulant treatment, Doppler echo was performed with a control of the blood, which was normal.

Conclusion: Thrombotic complications, although they are usually rare in pediatric patients with nephrotic syndrome (approx. 20%), should be diagnosed early through the clinic, imaging studies and laboratory with dosage of antithrombin III, platelet count and fibrinogen, avoiding major complications. Prophylaxis with anticoagulants is discussed, it is of great importance to balance risks and benefits of this.

 

Keywords: Nephrotic Syndrome; Thrombosis; Thromboembolic Complications

References

  1. Raymond Lin., et al. “A Systematic Review of Prophylactic. Anticoagulation in Nephrotic Syndrome”. 21Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, New South Wales, Australia; and 2 School of Medicine and Public Health, University of Newcastle, New South Wales, Australia. Kidney International Reports 5 (2020): 435-447.
  2. Yan-Li Lv., et al. “Spectrum of thrombotic complications and their outcomes in Chinese children with primary nephrotic syndrome”. Italian Journal of Pediatrics 46 (2020): 182.
  3. James McCaffrey., et al. “The non-immunosuppressive management of childhood nephrotic syndrome”. Pediatric Nephrology 31 (2016): 1383-1402.
  4. Geeta Gyamlani., et al. “Association of serum albumin level and venous thromboembolic events in a large cohort of patients with nephrotic syndrome”. 21Nephrology Section, Memphis Veterans Affairs Medical Center, Memphis, TN, USA, 2Division of Nephrology, University of Tennessee, Health Science Center, Memphis, TN, USA and 3Division of Nephrology, University of California, Irvine, CA, USA”. Nephrol Dial Transplant 32 (2017): 157-164.
  5. “KDIGO Clinical Practice Guideline for Glomerulonephritis” (2019).
  6. Bryce A Kerlin., et al. “Venous thromboembolism in pediatric nephrotic syndrome”. Department of Pediatrics, Division of Nephrology, Nationwide Children’s Hospital, Columbus, OH, USA”. Pediatric Nephrology 29.6 (2014): 989-997.
  7. Bryce A Kerlin., et al. “Epidemiology and Pathophysiology of Nephrotic Syndrome–Associated Thromboembolic Disease”. Clinical Journal of the American Society of Nephrology 7 (2012): 513-520.

Citation

Citation: Ceballos Gabriela E., et al. “Venous thrombosis as a complication of primary Nephrotic Syndrome". Acta Scientific Paediatrics 5.9 (2022): 00-00.

Copyright

Copyright: © 2022 Ceballos Gabriela E., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor1.197

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