Acta Scientific PAEDIATRICS (ISSN: 2581-883X)

Mini Review Article Volume 5 Issue 9

Endometrial Aromatase and Effect on Endometrial Implantation in Postmenopausal Patients

Shawky Badawy*

Department of Obstetrics and Gynecology, Upstate Medical University, Syracuse, New York

*Corresponding Author: Shawky Badawy, Department of Obstetrics and Gynecology, Upstate Medical University, Syracuse, New York.

Received: July 20, 2022; Published: August 12, 2022

Abstract

Aromatase is an enzyme that converts testosterone to estradiol and androstenedione to estrone. Studies showed that this enzyme is present in endometriosis cells and the eutopic endometrium of these patients [1]. However, aromatase is not present in the normal endometrium. It is suggested that aromatase in the endometrium helps the growth and implantation of the endometrium in various locations leading to the development of endometriosis [2]. Biopsies taken from endometrium of patients that have no endometriosis, did not show any aromatase. This can be used as a test to check if patients have endometriosis.

 

Keywords: Endometrial; Aromatase; Implantation; Postmenopausal

References

  1. Noble LS., et al. “Aromatase Expression in Endometriosis”. Journal of Clinical Endocrinology and Metabolism 81 (1996): 176-179.
  2. Zeitoun KM and Bulun SE. “Aromatase: A key Molecule in the Pathophysiology of Endometriosis and a Therapeutic Target”. Fertility and Sterility 72 (1999): 961-969.
  3. Edgar Haydon. “Postmenopausal Endometriosis in 78-year-Old Woman”. Surgery, Gynecology and Obstetrics 111 (1960): 348-356.
  4. Kempers RD., et al. “Significant Postmenopausal Endometriosis”. Surgery, Gynecology and Obstetrics 111 (1960): 348-356.
  5. Punnonen R., et al. “Postmenopausal Endometriosis”. European Journal of Obstetrics and Gynecology and Reproductive Biology 11 (1980): 195-200.

Citation

Citation: Shawky Badawy. “Endometrial Aromatase and Effect on Endometrial Implantation in Postmenopausal Patients". Acta Scientific Paediatrics 5.9 (2022): 13-14.

Copyright

Copyright: © 2022 Shawky Badawy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor1.197

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