Acta Scientific Paediatrics (ISSN: 2581-883X)

Editorial Volume 5 Issue 7

Vitamin D - A Fundamental Paradigm Shift in Pediatrics?

Abdul Halim Abdul Jalil*

KPJ Ampang Puteri Specialist Hospital, Selangor, Malaysia

*Corresponding Author: Abdul Halim Abdul Jalil, KPJ Ampang Puteri Specialist Hospital, Selangor, Malaysia.

Received: May 19, 2022; Published:


Vitamin D deficiency/insufficiency in reality is a pandemic that is frequently undiagnosed and untreated [1-3] Research findings to date appear persuasive enough for clinicians to reconsider current clinical applicability of vitamin D supplementation.

The major source of vitamin D3 (cholecalciferol) in the body is an endogenous, naturally occurring phytochemically produced steroidal molecule. This is biologically inactive and requires enzymatic conversion to active metabolites. The plant source vitamin D2 (ergocalciferol) is less efficient and more toxic. and will not be referred to in this paper. Vitamin D3 is converted enzymatically in the liver to 25-hydroxyvitamin D (25[OH]D), the major circulating form of vitamin D, and then in the kidney to 1,25-dihydroxyvitamin D, the active form of vitamin D.


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  10. Iacopo Chiodini., et al. “Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes”. Systematic review article”. Frontiers in Public Health (2021).
  11. Ashu Rastogi., et al. “Short term, high-dose vitamin D supplementation for COVID-19 disease: a randomised, placebo-controlled, study (SHADE study)”. Postgraduate Medical Journal1156 (2020).


Citation: Abdul Halim Abdul Jalil. “Vitamin D - A Fundamental Paradigm Shift in Pediatrics?”. Acta Scientific Paediatrics 5.7 (2022): 00-00.


Copyright: © 2022 Abdul Halim Abdul Jalil. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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