MP Narayanan

Senior Resident, Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India

*Corresponding Author: MP Narayanan, Senior Resident, Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.

Received: February 28, 2022; Published: February 28, 2022

Abstract

Congenital metabolic disorders/Inherited metabolic disorders caused by deficiency of enzymes which result in substrate accumulation and cause mild or sever neurologic/psychological manifestations. This leads to death or permanent disability of the child. Some forms IEMs cause isolated stable mental retardation (MR) and global developmental delay [1]. About 25 million babies were born per year and infant mortality rate of 35 /1000 live births were reported in India [2]. Around 500 inborn errors of metabolism (IEM) were present in Indian population and it is stated that 1:20 Indian have some form of disorder or birth defects [3]. Pooled birth prevalence of IEM in the Eastern Mediterranean region is about 75.7/100 000 live births. Total fatality rate in developing countries is 33% accounting for 0.4% of child deaths all over the world.

References

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2. Kamath and SSachidananda. "Reducing the infant mortality rate of India to 20 by 2020: Together we can do”. Indian Pediatrics 52.3 (2015): 193-194.
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6. ICMR Task Force on Inherited Metabolic Disorders. drseemakapoor@ gmail. com Rita Christopher A. Radha Rama Devi Madhulika Kabra Seema Kapoor Roli Mathur Mamta.
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Citation

Citation: MP Narayanan. “Inherited Metabolic Disorders - Relevance of Newborn Screening in India”. Acta Scientific Paediatrics 5.3 (2022): 25-26.

Copyright

Copyright: © 2022 MP Narayanan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.