Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 5 Issue 3

A Transient form of Insulin-Requiring Diabetes Mellitus on a 15-Year-Old with Wolf-Hirschhorn Syndrome

Ana Bernardo Ferreira1*, Teresa Amaral Pinheiro1, Ana Luísa Barbosa2, Catarina Matos de Figueiredo1, Sara Oliveira1 and Sónia Aires1

1Pediatrics and Neonatology Department, Centro Hospitalar de Entre-o-Douro e Vouga, Portugal
2Internal Medicine Department, Centro Hospitalar de Entre-o-Douro e Vouga, Portugal

*Corresponding Author: Ana Bernardo Ferreira, Pediatrics and Neonatology Department, Centro Hospitalar de Entre-o-Douro e Vouga, Portugal.

Received: January 12, 2022; Published: February 25, 2022

Abstract

Wolf-Hirschhorn Syndrome is a rare disorder caused by a deletion in the short arm of chromosome 4. Depending on the genetic defect, phenotype variability can be extensive, with multi-systemic involvement. Diabetes mellitus classification depends on clinical characteristics, clinical course, and laboratory findings and has important implications. The authors report a case of a 15-year-old girl with Wolf-Hirschhorn Syndrome, who presented with Hyperglycemic Hyperosmolar Status and was diagnosed with diabetes. Insulin treatment was suspended four years after the diagnosis. The complexity of the case and the difficulties on classifying and understanding this transient form of pancreatic endocrine insufficiency are discussed.

Keywords: Wolf-Hirschhorn Syndrome; Diabetes Mellitus; Hyperglycemic Hyperosmolar Status; Diabetic Ketoacidosis; Transient Pancreatic Insufficiency

References

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Citation

Citation: Ana Bernardo Ferreira., et al. “A Transient form of Insulin-Requiring Diabetes Mellitus on a 15-Year-Old with Wolf-Hirschhorn Syndrome”. Acta Scientific Paediatrics 5.3 (2022): 03-06.

Copyright

Copyright: © 2022 Ana Bernardo Ferreira., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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