Acta Scientific Paediatrics (ISSN: 2581-883X)

Case Report Volume 4 Issue 12

A Preterm Newborn with Spontaneous Intestinal Perforation Managed with Non-surgical Approach

Shivendra P Singh1, Kirti M Naranje1*, Anita Singh1 and Vijay Upadhyay2

1Department of Neonatology, SGPGI, Lucknow (UP), India

22Department of Pediatric Surgery, SGPGI, Lucknow (UP), India

*Corresponding Author: Kirti M Naranje, Department of Neonatology, SGPGI, Lucknow (UP), India.

Received: October 25, 2021; Published: November 26, 2021


A male 1255 gm neonate, first of the twins was born to a 35 year old gravidae 3 mother via emergency caesarean section at 34 weeks of gestation in view of premature rupture of membranes and previous caesarean section. Antenatally , this was a triplet pregnancy with one fetus reduced at 11 weeks of gestation. A full course of antenatal corticosteroid therapy was administered. The Apgar score was 8 at both 1 and 5min. The infant was admitted to the neonatal intensive care unit in view of prematurity, low birth weight and history of leaking PV in mother 5 days prior to LSCS. A venous umbilical catheter was placed, and sepsis screen was sent. He was started on ampicillin and gentamicin. Parenteral nutrition was initiated, and minimal enteral feeding with formula milk via orogastric tube was started within first 24 hours of life. Feeding intolerance was noted in form of significant greenish residual aspirates following which feeding was stopped and antibiotics were upgraded to meropenem and colistin. The first passage of meconium occurred within 24 hours of life. Abdominal distension along with a bluish discoloration was noted on day 3. Haemodynamic instability along with thrombocytopenia was also observed for which the baby received 2 units of platelet transfusion. Abdominal radiograph was suggestive of pneumoperitoneum, hence differentials of spontaneous intestinal perforation and necrotising enterocolitis (NEC) was suspected, and enteral feeding was discontinued. Serial abdominal radiographs were obtained and were conclusive of pneumoperitoneum hence appropriate empirical antibiotic treatment with vancomycin, cefotaxime and metronidazole was initiated and an abdominal drain was inserted at day 6 of life following which abdomen became soft and baby was passing stools 1 to 2 times in a day. Baby was initially being managed on room air but at day 11 of life was put on CPAP in view of respiratory distress and apnoea episodes and was gradually weaned off in next 48 hours, EBM feeds were restarted at day 25 of life and with conservative management appropriate weight gain of the baby was observed.

Keywords: Newborn; Spontaneous Intestinal Perforation (SIP); Necrotising Enterocolitis (NEC)


  1. Wadhawan R., et al. “Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis”. Journal of Perinatology 34 (2014): 64-70.
  2. Holland AJ., et al. “Small bowel perforation in the premature neonate: congenital or acquired?” Pediatric Surgery International 19 (2003): 489-494.
  3. Shah J., et al. “Intestinal perforation in very preterm neonates: risk factors and outcomes”. Journal of Perinatology 35 (2015): 595-600.


Citation: Kirti M Naranje., et al. “A Preterm Newborn with Spontaneous Intestinal Perforation Managed with Non-surgical Approach". Acta Scientific Paediatrics 4.12 (2021): 31-32.


Copyright: © 2021 Kirti M Naranje., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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