Acta Scientific Paediatrics (ISSN: 2581-883X)

Review Article Volume 4 Issue 2

The Role of Brainstem Sensitization in the Pathophysiology of Deformational Plagiocephaly

Rene J Zweedijk*

Member of the Dutch Osteopathic Association, Director of Pro-Osteo, Responsible for the Osteopathic Pediatric Education Netherlands, The Netherlands

*Corresponding Author: Rene J Zweedijk, Member of the Dutch Osteopathic Association, Director of Pro-Osteo, Responsible for the Osteopathic Pediatric Education Netherlands, The Netherlands.

Received: January 21, 2021; Published: January 29, 2021

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Abstract

Deformational Plagiocephaly (DP) is a common clinical presentation. There is no consensus as to the aetiology of DP, there is no risk factor that is uniformly considered as dominant. The consensus about the pathogenetic factors that are important in the onset of DP is more robust. Most cases are presented with no skull deformity at birth and most problems seem to appear at the age of two months. This implies that postnatal factors have an influence on the onset of DP. Prolonged back-laying position in combination with a restriction in motion of the upper neck area are generally considered as important factors in the onset of DP. The restriction in motion can be caused by muscular and neurological reasons. The purpose of this article is to present an aetiology model as to the neurological aspects that may be causing plagiocephaly and how osteopathy may potentially influence the amelioration of plagiocephaly. Sensitization of the upper neck and brainstem may be caused by intrauterine positioning, traumatic birth processes or prolonged pressure on specific areas of the skull. This sensitization will increase sensitivity of touch-, pressure- and pain-fibers, muscle tone, impair muscle function and enhance postural and birth survival reflexes. The postural reflexes, in combination with impaired muscle function and the prolonged supine positioning of the infant, play a crucial role in the progress of some types of Deformational Plagiocephaly (DP). These neurological considerations should be analyzed and treated by osteopaths and allied professions when faced with DP.

Keywords: Deformational Plagiocephaly; Brainstem; Aetiology

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References

  1. Lennartsson F and Nordin P. “Nonsynostotic plagiocephaly: a child health care intervention in Skaraborg, Sweden”. BMC Pediatrics 1 (2019): 48.
  2. Ghizoni E., et al. “Diagnosis of infant synostotic and nonsynostotic cranial deformities: a review for pediatricians”. Revista Paulista de Pediatria 4 (2016): 495-502.
  3. De Bock F., et al. “Deformational plagiocephaly in normal infants: a systematic review of causes and hypotheses”. Archives of Disease in Childhood 6 (2017): 535-542.
  4. Collett BR., et al. “Cognitive Outcomes and Positional Plagiocephaly”. Pediatrics 2 (2019).
  5. Argenta L., et al. “Clinical classification of positional plagiocephaly”. Journal of Craniofacial Surgery 3 (2004): 368-372.
  6. Captier G., et al. “Classification and pathogenic models of unintentional postural cranial deformities in infants: plagiocephalies and brachycephalies”. Journal of Craniofacial Surgery1 (2011): 33-41.
  7. Lessard S., et al. “Exploring the impact of osteopathic treatment on cranial asymmetries associated with nonsynostotic plagiocephaly in infants”. Complementary Therapies in Clinical Practice 4 (2011): 193-198.
  8. van Vlimmeren LA., et al. “Risk factors for deformational plagiocephaly at birth and at 7 weeks of age: a prospective cohort study”. Pediatrics 2 (2007): e408-418.
  9. Cavalier A., et al. “Prevention of deformational plagiocephaly in neonates”. Early Human Development 8 (2011): 537-543.
  10. Xiong Z., et al. “Unique finding in congenital muscular torticollis: Clinic screening on the neck of one day old neonate and ultrasonographic imaging from birth through 3 years of follow-up”. Medicine (Baltimore)11 (2019): e14794.
  11. Han MH., et al. “Comparison of Clinical Findings of Congenital Muscular Torticollis Between Patients With and Without Sternocleidomastoid Lesions as Determined by Ultrasonography”. Journal of Pediatric Orthopaedics (2017).
  12. Golden KA., et al. “Sternocleidomastoid imbalance versus congenital muscular torticollis: their relationship to positional plagiocephaly”. Cleft Palate-Craniofacial Journal 3 (1999): 256-261.
  13. Herman MJ. “Torticollis in infants and children: common and unusual causes”. Instructional Course Lectures 55 (2006): 647-653.
  14. Hruby RJ., et al. “The five osteopathic models: rationale, application, integration: from an evidence-based to a person-centered osteopathy” (2017).
  15. Bolay H and Moskowitz MA. “Mechanisms of pain modulation in chronic syndromes”. Neurology 59 (2002): S2-7.
  16. Dux M., et al. “TRP Channels in the Focus of Trigeminal Nociceptor Sensitization Contributing to Primary Headaches”. International Journal of Molecular Sciences 1 (2020).
  17. Noseda R., et al. “Non-Trigeminal Nociceptive Innervation of the Posterior Dura: Implications to Occipital Headache”. Journal of Neuroscience 10 (2019): 1867-1880.
  18. Roldan-Jimenez C., et al. “Central Sensitization in Chronic Musculoskeletal Pain Disorders in Different Populations: A Cross-Sectional Study”. Pain Medicine (2020).
  19. Neuhuber W., et al. “Manuelle Medizin 1: Fehlfunktion und Schmerz am Bewegungsorgan verstehen und behandeln”. (2015): 357-362.
  20. Böhni UW., et al. “Manuelle Medizin 1 : Fehlfunktion und Schmerz am Bewegungsorgan verstehen und behandeln”. (2015): 365-372.
  21. Lekhel H., et al. “Postural responses to vibration of neck muscles in patients with idiopathic torticollis”. Brain 120 (1997): 583-591.
  22. Lee SH., et al. “Macroscopic Innervation of the Dura Mater Covering the Middle Cranial Fossa in Humans Correlated to Neurovascular Headache”. Frontiers in Neuroanatomy 11 (2017): 127.
  23. Lv X., et al. “Innervation of the cerebral dura mater”. Neuroradiology Journal 3 (2014): 293-298.
  24. Zhang J., et al. “Jaw muscle spindle afferents coordinate multiple orofacial motoneurons via common premotor neurons in rats: an electrophysiological and anatomical study”. Brain Research 1489 (2012): 37-47.
  25. Zhang J., et al. “Monosynaptic circuitry of trigeminal proprioceptive afferents coordinating jaw movement with visceral and laryngeal activities in rats”. Neuroscience 2 (2005): 497-505.
  26. Xiong G and Matsushita M. “Upper cervical afferents to the motor trigeminal nucleus and the subnucleus oralis of the spinal trigeminal nucleus in the rat: an anterograde and retrograde tracing study”. Neuroscience Letter 2 (2000): 127-130.
  27. Saxon DW and Hopkins DA. “Efferent and collateral organization of paratrigeminal nucleus projections: an anterograde and retrograde fluorescent tracer study in the rat”. Journal of Comparative Neurology 1 (1998): 93-110.
  28. Dunville LM and Kramer J. “Oculocardiac Reflex”. In: Treasure Island (FL) (2020).
  29. King HH., et al. “The Science and Clinical Application of Manual Therapy” (2014).
  30. Kontzialis M and Kocak M. “Imaging evaluation of trigeminal neuralgia”. Journal of Istanbul University Faculty of Dentistry 51 (2017): S62-S68.
  31. Tekes A., et al. “Birth-related injury to the head and cervical spine in neonates”. Magnetic Resonance Imaging Clinics of North America 4 (2011): 777-790.
  32. Sergueef N., et al. “Palpatory diagnosis of plagiocephaly”. Complementary Therapies in Clinical Practice 2 (2006): 101-110.
  33. Ekeus C., et al. “Neonatal complications among 596 infants delivered by vacuum extraction (in relation to characteristics of the extraction)”. Journal of Maternal-Fetal and Neonatal Medicine 18 (2018): 2402-2408.
  34. Andrews MAW. “Stretch Receptor and Somatic Dysfunction: A Narrative Review”. Journal of the American Osteopathic Association 8 (2019): 511-519.
  35. Burstein R., et al. “Neurobiology of Photophobia”. Journal of Neuroophthalmology 1 (2019): 94-102.
  36. Terry EL., et al. “Standardizing procedures to study sensitization of human spinal nociceptive processes: comparing parameters for temporal summation of the nociceptive flexion reflex (TS-NFR)”. International Journal of Psychophysiology 3 (2011): 263-274.
  37. Noseda R., et al. “Current understanding of photophobia, visual networks and headaches”. Cephalalgia 13 (2019): 1623-1634.
  38. Travagli RA and Anselmi L. “Vagal neurocircuitry and its influence on gastric motility”. Nature Reviews Gastroenterology and Hepatology 7 (2016): 389-401.
  39. Moller M and May A. “The unique role of the trigeminal autonomic reflex and its modulation in primary headache disorders”. Current Opinion in Neurology 3 (2019): 438-442.
  40. Babic T., et al. “Differential organization of excitatory and inhibitory synapses within the rat dorsal vagal complex”. American Journal of Physiology-Gastrointestinal and Liver Physiology 1 (2011): G21-32.
  41. Shevell M. “The tripartite origins of the tonic neck reflex: Gesell, Gerstmann, and Magnus”. Neurology 9 (2009): 850-853.
  42. Gieysztor EZ., et al. “Persistence of primitive reflexes and associated motor problems in healthy preschool children”. Archives of Medical Science 1 (2018): 167-173.
  43. Seffinger MA. American Osteopathic A. “Foundations of osteopathic medicine: philosophy, science, clinical applications, and research” (2018).
  44. Sargent B., et al. “Congenital Muscular Torticollis: Bridging the Gap Between Research and Clinical Practice”. Pediatrics 2 (2019).
  45. Gieysztor EZ., et al. “Trunk rotation due to persistence of primitive reflexes in early school-age children”. Advances in Clinical and Experimental Medicine 3 (2018): 363-366.
  46. Magoun HI., et al. “Osteopathy in the cranial field”. [Fort Worth, Tex.]: Sutherland Cranial Teaching Foundation (1997).
  47. Oh AK., et al. “Predictors of Severity in Deformational Plagiocephaly”. Journal of Craniofacial Surgery 20 (2009): 685-689.
  48. Branch LG., et al. “Argenta clinical classification of deformational plagiocephaly”. Journal of Craniofacial Surgery 263 (2015): 606-610.
  49. Purzycki A., et al. “Incidence of otitis media in children with deformational plagiocephaly”. Journal of Craniofacial Surgery5 (2009): 1407-1411.
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Citation

Citation: Rene J Zweedijk. “The Role of Brainstem Sensitization in the Pathophysiology of Deformational Plagiocephaly".Acta Scientific Paediatrics 4.2 (2021): 57-65.




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