Acta Scientific Paediatrics (ISSN: 2581-883X)

Review Article Volume 4 Issue 1

Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I

Iliana Karagkouni1, Maria Sideridou2,3, Stavroula Stoupi1 and Georgios Efthimiou4*

1Department of Dietetics, Metropolitan College, Athens, Greece
2Department of Biomedical Sciences, Metropolitan College, Athens, Greece
3Department of Nutrition and Dietetics, Hellenic Mediterranean University, Greece
4Department of Biomedical and Forensic Sciences, Hardy Building, University of Hull, United Kingdom

*Corresponding Author: Georgios Efthimiou, Department of Biomedical and Forensic Sciences, Hardy Building, University of Hull, United Kingdom.

Received: November 09, 2020; Published: December 29, 2020

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Abstract

The role of breastfeeding and dietary habits was studied in 10 children with DM I (case group) and compared with 10 healthy controls. Our results showed that the case group had significantly shorter exclusive breastfeeding duration compared with the control group (p = 0.006). An in silico comparative analysis of gut microbiota data from two recent studies was also performed in order to identify any specific bacterial genera potentially associated with DM I, due to prolonged breastfeeding. The Pasteurellaceae family, found in breast milk, was shown to have a significantly higher population in the intestine in the control group (p = 0.010). Overall, this preliminary study showed that exclusive breastfeeding duration is strongly associated with DM I. An association between breast milk microbiome and gut microbiome was also observed. This should encourage further research, aiming to examine both the effect of breastfeeding on gut microbiome and the possible links with DM I.

Keywords: Diabetes Mellitus Type I; Breastfeeding; Gut Microbiota

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Citation

Citation: Georgios Efthimiou., et al. “Association Between Breastfeeding and the Development of Childhood Diabetes Mellitus Type I (DM I): The Effect of Prolonged Exclusive Breastfeeding on Gut Microbiome and the Link with DM I”. Acta Scientific Paediatrics 4.1 (2021): 28-32.




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