Acta Scientific Paediatrics (ISSN: 2581-883X)

Research Article Volume 3 Issue 11

The Effect of Inter-Pregnancy Interval on the Recurrence Rate of Spontaneous Preterm Birth among Women who Delivered at KCMC Hospital, Tanzania: A Registry-based Cohort Study

Sophia Kiwango1*, Pendo Mlay1, Kiondo S Kiondo1, Caroline Amour2, Innocent B Mboya2,3 and Michael J Mahande2

1Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania
2Department of Epidemiology and Biostatistics, Institute of Public Health, Kilimanjaro Christian Medical University College (KCMUCo), Moshi, Tanzania
3School of Mathematics, Statistics, and Computer Science, University of KwaZulu-Natal, Pietermaritzburg, South Africa

*Corresponding Author: Sophia Kiwango, Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Centre (KCMC), Moshi, Tanzania.

Received: September 05, 2020; Published: October 28, 2020

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Abstract

Background: Inter pregnancy interval has been associated with adverse neonatal outcomes, including preterm birth and low birth weight. Little is known on the effect of Interpregnancy interval on the recurrence of preterm birth. This study aimed to determine the effect of Interpregnancy interval on the recurrence of spontaneous preterm birth among women who delivered at KCMC hospital, Northern Tanzania.

Methods: We conducted a retrospective cohort study using maternally-linked birth registry data from all recorded women who delivered two consecutive singleton pregnancies and spontaneous preterm birth in their first pregnancy from 2005 - 2015 at KCMC referral hospital. The outcome was the recurrence of spontaneous preterm birth and IPI was the primary exposure of interest. We analyzed data using STATA version 15 and estimated the relative risk and recurrence risk of spontaneous preterm birth with 95% confidence intervals using the log-binomial regression model at a 5% statistical significance level.

Results: The recurrence rate of spontaneous preterm was 23.1%. IPI of ≥ 60, 18 - 23 and 12 - 17 months were associated with lower risk (RR: 0.79; 95%CI 0.53 - 1.16), (RR: 0.78; 95%CI 0.54 - 1.13) and (RR: 0.92; 95%CI 0.65 - 1.31) of SPTB in the subsequent pregnancies compared to 24-59 months. However, these associations were not statistically significant. On the other hand, inadequate (< 4) ANC visits during pregnancy significantly increased the risk of SPTB (RR: 3.98; 95%CI: 3.05 - 5.20) in the subsequent pregnancy.

Conclusion: The recurrence of SPTB is high among women in this study. The short and long IPI were all protective against the risk of recurrence SPTB while inadequate (< 4) ANC visits increased the risk. Interventions to promote optimal Interpregnancy interval and close follow-up of women at risk, especially during ANC visits, may reduce the risk of recurrence of preterm birth and associated adverse outcomes.

Keywords: Inter-Pregnancy Interval; Recurrence Risk; Spontaneous Preterm Birth; Tanzania

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References

  1. Report of a WHO Technical Consultation on Birth Spacing (2005).
  2. Mahande MJ and Obure J. “Effect of interpregnancy interval on adverse pregnancy outcomes in northern Tanzania: A registry-based retrospective cohort study”. BMC Pregnancy Childbirth1 (2016).
  3. Koullali B., et al. “The Effect of Interpregnancy Interval on the Recurrence Rate of Spontaneous Preterm Birth: A Retrospective Cohort Study”. The American Journal of Perinatology 2 (2017): 174-182.
  4. Temu TB., et al. “Maternal and obstetric risk factors associated with preterm delivery at a referral hospital in northern-eastern Tanzania”. Asian Pacific Journal of Reproduction 5 (2016): 365-370.
  5. Ball SJ., et al. “Re-evaluation of link between interpregnancy interval and adverse birth outcomes: Retrospective cohort study”. British Medical Journal 349 (2014): g4333.
  6. Hsieh T., et al. “The Impact of Interpregnancy Interval and Previous Preterm Birth on the Subsequent Risk of Preterm Birth” (2004).
  7. Mahande MJ., et al. “Recurrence of preeclampsia in Northern Tanzania: A registry-based cohort study”. PLoS One11 (2013): 1-9.
  8. Global T, Report A. Born Too Soon.
  9. Mahande MJ., et al. Recurrence of preterm birth and perinatal mortality in northern Tanzania: registry-based cohort study 18.8 (2013): 962-967.
  10. Mech LD. “A Gray Wolf (Canis lupus) Delivers Live Prey to a Pup”. Canadian Field-Naturalist 2 (2014): 189-190.
  11. Janša V., et al. “The impact of inter-pregnancy interval on subsequent risk of preterm birth The impact of inter-pregnancy interval on subsequent risk of preterm birth”. The Journal of Maternal-Fetal and Neonatal Medicine (2017).
  12. Anku L., et al. “Inter-pregnancy interval and associated adverse maternal outcomes among women who delivered at Kilimanjaro Christian Medical Centre in Tanzania 2000-2015”. Plos one (2020): 1-15.
  13. Conde-agudelo A., et al. “Effects of Birth Spacing on Maternal, Perinatal , Infant , and Child Health : A Systematic Review of Causal Mechanisms”. Studies in Family Planning 2 (2012): 93-114.
  14. Ratzon R., et al. “The role of prenatal care in recurrent preterm birth”. European Journal of Obstetrics and Gynecology 1 (2011): 40-44.
  15. World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience. Geneva: World Health Organization (2016).
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Citation

Citation: Sophia Kiwango., et al. "The Effect of Inter-Pregnancy Interval on the Recurrence Rate of Spontaneous Preterm Birth among Women who Delivered at KCMC Hospital, Tanzania: A Registry-based Cohort Study". Acta Scientific Paediatrics 3.11 (2020): 59-65.




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