Acta Scientific Paediatrics (ISSN: 2581-883X)

Newsletter Volume 3 Issue 5

Introducing the One-Pot-Amine-Thiol-Ene Reaction to Develop Redox Responsive Nanocarriers for its Potential Use in Anticancer Drug Release

Sayan Basak*

Department of Polymer Science and Technology, University of Calcutta, Kolkata, West Bengal, India>

*Corresponding Author: Sayan Basak, Department of Polymer Science and Technology, University of Calcutta, Kolkata, West Bengal, India.

Received: March 20, 2020; Published: April 16, 2020

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  The aim to protect the healthy cells remains one of the prime challenges while designing an anticancer drug and its delivery pathway. With the advent of advanced nanocarriers coupled with stimuli-responsive polymer frameworks, the drug-loaded matrix can efficiently deliver the drug with a negligible impact on the healthy cells. The reinforced linkages (ionic and covalent) between the drug molecule and the polymer help in an enhanced encapsulation, thereby minimizing the faulty delivery and increasing the overall efficacy of the process. Furthermore, the integration of stimuli-responsive properties tunes the material to exhibit more precise functionalities, such as reputing of the polymer network at the desired location when excited with a specific stimulus, harmonizes the process to deliver drug molecules very precisely.

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Citation

Citation: Sayan Basak. “Introducing the One-Pot-Amine-Thiol-Ene Reaction to Develop Redox Responsive Nanocarriers for its Potential Use in Anticancer Drug Release”. Acta Scientific Paediatrics 3.5 (2020): 03-04.




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