` Acta Scientific | International Open Library | Open Access Journals Publishing Group

Acta Scientific Orthopaedics (ISSN: 2581-8635)

Case Report Volume 9 Issue 1

Bilateral Medial Patellofemoral and Medial Patellotibial Ligament Reconstruction in a Patient with Nails Pattela Syndrome – A Rare Case and Review of the Literature

João Luis Afonso Martins* and Francisco Serdoura and Paulo Oliveira

Department of Orthopedics and Traumatology, ULS São João, Porto, Portugal

*Corresponding Author: João Luis Afonso Martins, Department of Orthopedics and Traumatology, ULS São João, Porto, Portugal.

Received: November 24, 2025; Published: December 15, 2025

Abstract

Nail-patella syndrome (NPS), is an infrequent inherited dysplasia that primarily involves structural underdevelopment of the nails and patellae. Patellar instability is a prevalent manifestation in NPS and, in many cases, necessitates stabilisation through surgical means. Although the majority of published work on the knee involvement in this syndrome concentrates on its clinical presentation and radiographic features, there is limited literature addressing surgical management. This case report details a 19-year-old male diagnosed with NPS, who presented with bilateral anterior knee pain and demonstrated recurrent patellar dislocations affecting both knees. The present study describes a patient with NPS treated surgically by reconstruction of the medial patellofemoral (MPFL) and medial patellotibial ligaments (MPTL) bilaterally with excellent clinical and functional results.

Keywords: Knee; Nails Patella Syndrome; Patellofemoral Reconstruction

References

  1. Sweeney E., et al. “Nail patella syndrome: A review of the phenotype aided by developmental biology”. Journal of Medical Genetics 40 (2003): 153-162.
  2. Romero P., et al. “c.194 A>C (Q65P) mutation in the LMX1B gene in patients with nail-patella syndrome associated with glaucoma”. Molecular Vision 17 (2011): 1929-1939.
  3. Witzgall R. “How are podocytes affected in nail-patella syndrome?” Pediatric Nephrology 23 (2008): 1017-1020.
  4. Granata A., et al. “Nail-patella syndrome and renal involvement. Description of three cases and literature review”. Clinical Nephrology 69 (2008): 377-382.
  5. Turner JW. “An hereditary arthrodysplasia associated with hereditary dystrophy of the nails”. JAMA 100 (1933): 882-884.
  6. Choczaj-Kukula A and Janniger CK. “Nail-patella syndrome”. In emedicine: WebMD (2024).
  7. Scuderi G., et al. “Lateral release and proximal realignment for patellar subluxation and dislocation. A long-term follow-up”. The Journal of Bone and Joint Surgery 70 (1988): 856-861.
  8. Brown DE., et al. “The Elmslie-Trillat procedure: Evaluation in patellar dislocation and subluxation”. American Journal of Sports Medicine 12 (1984): 104‐109.
  9. Yubao Gong., et al. “Treatment of patellar instability in a case of hereditary onycho-osteodysplasia (nail-patella syndrome) with medial patellofemoral ligament reconstruction: A case report”. 11.6 (2016): 2361-2364.

Citation

Citation: João Luis Afonso Martins., et al. “Bilateral Medial Patellofemoral and Medial Patellotibial Ligament Reconstruction in a Patient with Nails Pattela Syndrome – A Rare Case and Review of the Literature".Acta Scientific Orthopaedics 9.1 (2026): 22-28.

Copyright

Copyright: © 2026 João Luis Afonso Martins., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days

Indexed In



News and Events


  • Publication Certificate
    Authors will be provided with the Publication Certificate after their successful publication
  • Last Date for submission
    Authors are requested to submit manuscripts on/before January 05, 2025, for the Second issue of 2026.

Contact US