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Acta Scientific Orthopaedics (ISSN: 2581-8635)

Research Article Volume 8 Issue 9

Association of Dentoskeletal Malocclusions with ABO Blood Groups: A Cross-Sectional Study

Shruti Mathur* and Anup Kanase

Department of Orthodontics and Dentofacial Orthopaedics, MAIDSIDU, India

*Corresponding Author: Shruti Mathur, Department of Orthodontics and Dentofacial Orthopaedics, MAIDSIDU, India.

Received: May 26, 2025; Published: August 23, 2025

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Abstract

Background: Malocclusion has a multifactorial aetiology and can be attributed to local as well as general factors. Genetics plays a significant role in aetiology of malocclusion. Malocclusion is considered as a quantitative genetic trait with continuous graded distribution in the population. Association between various oral diseases with ABO blood groups have been established in the past. ABO blood groups are one of the most important human genetic traits that follows Mendalian inheritance. Since both the ABO blood groups and malocclusion are genetic traits, authors have carried out studies to assess if association between the two exists. Cross sectional study was carried out is to assess the association between dental, skeletal malocclusions with the ABO blood groups.

Materials and Methods: This was a cross-sectional observational study conducted in 100 subjects in the range of 18-28 years. Standard pretreatment study models and lateral cephalograms were taken. Dental malocclusion was assessed from study models. Cephalograms were analyzed for three vertical skeletal cephalometric parameters which included FMA angle, Y -axis, Sn-GoGn Angle. Five sagittal cephalometric parameters which included ANB angle, WITS appraisal, App-Bpp, YEN angle and Beta angle. Blood group assessment was done using the point of care device Erycard2.0. Statistical analysis was done using IBM SPSS version 23 and p value ≤ 0.5.

Results: This study concluded that there was no statistically significant association between dentoskeletal malocclusions and ABO blood groups. Also, there is lack of data regarding any association between the genotypes of dental and skeletal malocclusions with alleles of ABO blood groups.

Keywords: Skeletal Malocclusion; Dental Malocclusion; ABO Blood Groups

References

  1. Houston WJ., et al. “A textbook of orthodontics”.1st Bristol (UK):Wright (1986).
  2. Kharbanda OP. “Orthodontics: Diagnosis and Management of Malocclusion and Dentofacial Deformities. 3rd edition”. New Delhi (India): Elsevier Health Sciences (2019): 35-51.
  3. Mossey PA. “The heritability of malocclusion: Part 1--Genetics, principles and terminology”. British Journal of Orthodontics 2 (1999): 103-113.
  4. Mossey PA. “The heritability of malocclusion: part 2. The influence of genetics in malocclusion”. British Journal of Orthodontics 3 (1999): 195-203.
  5. Pinkston JA and Cole P. “ABO blood groups and salivary gland tumors (Alabama, United States)”. Cancer Causes Control6 (1996): 572-574.
  6. Kaslick RS., et al. “Investigation of periodontosis with periodontitis: literature survey and findings based on ABO blood groups”. Journal of Periodontology  7 (1971): 420-427.
  7. Gheisari R., et al. “The association between blood groups and maxillofacial deformities”. Indian Journal of Plastic Surgery 2 (2008): 138-140.
  8. Sharma R., et al. “Association of ABO Blood Groups with Malocclusion in Population of Jaipur, India: a prospective study”. International Journal of Social Science Studies 11 (2015): 45-51.
  9. Gupta P., et al. “Correlation of ABO and Rh Blood Group with Dental Malocclusion in Population of Mysuru”. Dental Hypotheses2 (2020): 47.
  10. Rashid A and El Feky H. “Correlation between ABO Blood Groups and Malocclusion in a sample of Egyptian Populations: A cross sectional study”. Egyptian Dental Journal 65 (2019): 875-880.
  11. Al-Khatieeb MM., et al. “Association of ABO blood group and rhesus factor with dental malocclusion in a population of Baghdad, Iraq”. The International Journal of Medical Research and Health Sciences 7 (2018): 165-169.
  12. Shokor FF., et al. “Craniofacial morphology with genetic influence of abo blood group in Malaysian orthodontic patients”. International Journal of Pharma and Bio Sciences 4 (2015): 412-418.
  13. Gupta SP. “Association of ABO blood groups with occlusal pattern among Orthodontic patients of Kathmandu district”. The Journal of Medical Sciences 12 (2018): 2119-2129.
  14. Tariq B., et al. “Gender wise association between dental malocclusion classes and ABO blood group system”. Dentistry 532 (2019): 2161-3122.
  15. Rathi A., et al. “Association of ABO blood group with crowding among patients with different malocclusions”. Journal of Dentistry Defence Section 1 (2020): 4.
  16. Johns G. “Association of blood groups with malocclusion”. International Dental Journal of Student Research 3 (2021): 133-139.
  17. Datana SS and Bhandari S. “Correlating Vertical Skeletal Pat terns with ABO Blood Grouping System: A Cross-Sectional Study”. Journal of Contemporary Orthodontics3 (2019): 33-37.
  18. Schnibben CL. “A study of the relationships of the ABO human blood groups, the Rh Factor and hereditary malocclusions of the skeletal type, class II, division 1”. [Master's Thesis on theInternet].Chicago(US). Loyola University (1968).
  19. Flannery PM. “The ABO human blood groups and skeletal class III malocclusions. [ Master's Thesis on the Internet].Chicago(US). Loyola University (1969).
  20. Johns G. “Association of blood groups with malocclusion”. International Dental Journal of Student Research 3 (2021): 133-139.
  21. Kumar V and Sundareswaran S. “Cephalometric assessment of sagittal dysplasia: A review of twenty-one methods”. Journal of Indian Orthodontic Society 1 (2014): 33-41.
  22. Prasanth KA., et al. “Cephalometric Appraisal of Various Angles of Skeletal Discrepancy: A Systematic Review”. International Journal of Orthodontics 3 (2018).
  23. Ahmed M., et al. “Diagnostic performance of various cephalometric parameters for the assessment of vertical growth pattern”. Dental Press Journal of Orthodontics 4 (2016): 41-49.
  24. Dhruva G., et al. “Comparison of conventional tube agglutination method versus ERYCARD™ 2.0 for the ABO blood grouping system-A Pilot Study”. International Journal of Research in Medical Sciences 1 (2015): 59-61.
  25. Tiwari AK., et al. “Evaluation of new indigenous "point-of-care" ABO and Rh grouping device”. The Journal of Laboratory Physicians 1 (2018): 80-84.
  26. Roberts JA. “Blood groups and susceptibility to disease: A review”. British Journal of Preventive and Social Medicine 11 (1957): 107-125.
  27. Akhund IA., et al. “A study of relationship of ABO blood groups with myocardial infarction and angina pectoris”. Journal of Ayub Medical College, Abbottabad 4 (2001): 25-26.
  28. Koregol AC., et al. “ABO blood groups and Rhesus factor: an exploring link to periodontal diseases”. Indian Journal of Dental Research 3 (2010): 364-368.
  29. Vivek S., et al. “Association of ABO Blood Group and Rh factor with Periodontal Disease in a Population of Virajpet, Karnataka: A Cross-Sectional Study”. Journal of International Oral Health 4 (2013): 30-34.
  30. Cunha A., et al. “Genetic 73 variants in ACTN3 and MYO1H are associated with sagittal and vertical craniofacial skeletal patterns”. Oral Biology 97 (2019): 85-90.
  31. Huh A., et al. “Epigenetic influence of KAT6B and HDAC4 in the development of skeletal malocclusion”. American Journal of Orthodontics and Dentofacial Orthopedics 4 (2013): 568-576.
  32. da Fontoura CG., et al. “Candidate gene analyses of skeletal variation in malocclusion”. Journal of Dental Research 7 (2015): 913-920.

Citation

Citation: Alexandre Almeida., et al. “Revision of Aseptic Loosening Reverse Baseplate with Glenoid Bone Loss Using Alternative Scapular Spine Line Positioning".Acta Scientific Orthopaedics 8.9 (2025): 03-07.

Copyright

Copyright: © 2025 Alexandre Almeida., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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