Acta Scientific Orthopaedics (ISSN: 2581-8635)

Research Article Volume 7 Issue 10

Chondrofiller and Treatment of Cartilage Defects in the Knee

Rayeesa Faheem Syed1*, Rajesh Rachha2 and Srinivas Thati3

1MBBS, MS Orthopaedics, Arthroplasty Fellow, AIG Hospitals, Hyderabad, Telangana, India
2D-Ortho, FEBOT, FRCS (Tr and Orth), Senior consultant, AIG Hospitals, Hyderabad, Telangana, India
3MBBS, MS Orthopaedics, MRCS, FEBOT, FRCS (Tr and Orth), Senior consultant Director and HOD, Department of Orthopaedics, AIG Hospitals, Hyderabad, Telangana, India

*Corresponding Author: Rayeesa Faheem Syed, MBBS, MS Orthopaedics, Arthroplasty Fellow, AIG Hospitals, Hyderabad, Telangana, India.

Received: June 04, 2024; Published: September 20, 2024

Abstract

Background: Focal chondral defects of the knee are common. Several surgical techniques have been proposed for the management of chondral defects. In this study, early functional outcomes with use of Chondro Filler liquid in the knee articular cartilage defects were evaluated.

Methods: A retrospective study of 11 patients who underwent knee arthroscopy and ChondroFiller liquid application for ICRS Grade IV defects were followed up from 6 months to 18 months. Functional outcomes of the patients were evaluated from IKDC subjective evaluation forms.

Results: Mean age of patients was 46.6 years. Isolated chondral lesions were associated with better outcomes (Mean IKDC score 66.25). Chondral lesions are seen in association with other injuries in 63.64% of cases. Chondral lesions over medial femoral condyle are more common (81.8% ) and are associated with better outcomes when compared with lateral tibial plateau lesions. Female patients and high BMI were associated with poorer outcomes.

Conclusion: ChondroFiller liquid could serve as a good treatment option for Grade IV chondral defects in select patients. Future studies on bigger cohort could help in developing an algorithm for patient selection for use of ChondroFiller.

 Keywords: ChondroFiller; Cartilage Defects; Knee

Keywords: Ulnar Diamelia, Mirror Hand

References

  1. AJ Sophia Fox., et al. “The basic science of articular cartilage: structure, composition, and function”. Sports Health 1 (2009): 461-468.
  2. Weizel T Distler., et al. “Complex mechanical behavior of human articular cartilage and hydrogels for cartilage repair”. Acta Biomaterialia 118 (2020): 113-128.
  3. Karin Hjelle., et al. “Articular cartilage defects in 1,000 knee arthroscopies”. Arthroscopy7 (2002): 730-734.
  4. Curl WW., et al. “Cartilage injuries: a review of 31,516 knee arthroscopies”. Arthroscopy 13 (1997): 456-460.
  5. Schneider U. “Controlled, randomized multicenter study to compare compatibility and safety of ChondroFiller liquid (cell free 2-component collagen gel) with microfracturing of patients with focal cartilage defects of the knee joint”. Video Journal of Orthopaedics Surgery 1 (2016): 1-8.
  6. Jacek Mazek., et al. “Arthroscopic utilization of ChondroFiller gel for the treatment of hip articular cartilage defects: a cohort study with 12- to 60-month follow-up”. Journal of Hip Preservation Surgery1 (2021): 22-27.

Citation

Citation: Rayeesa Faheem Syed., et al. “Case Report on Ulna Diamelia (Mirror Hand) at St. Luke Catholic Hospital, Woliso".Acta Scientific Orthopaedics 7.10 (2024): 03-07.

Copyright

Copyright: © 2024 Rayeesa Faheem Syed., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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