Singh G¹, Agarwal VK²*, Narula RK³ and Somashekarappa T⁴

¹Resident, Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly (UP), India
²Assistant Professor, Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly (UP), India
³Professor, Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly (UP), India
⁴Professor and Head, Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly (UP), India

*Corresponding Author: Agarwal VK, Assistant Professor, Department of Orthopaedics, Rohilkhand Medical College and Hospital, Bareilly (UP), India.

Received: September 30, 2022; Published: March 02, 2023

Abstract

Background: To evaluate the reliability of Clinical, Radiological and Pathological signs in making the diagnosis of Musculoskeletal Tuberculosis and to identify alternative pathological conditions that resemble it.

Materials and Methods: This is a prospective study including a total of 110 patients. Clinical and Radiological examination of all patients was done followed by Percutaneous biopsy of the involved region. The obtained tissue samples were sent for histopathological examination as well as CBNAAT for making a definitive diagnosis of Musculoskeletal tuberculosis.

Results: The study included 110 cases. Males were involved more (65.5%) as compared to females (34.5%). Clinically and radiologically, the most common sites involved were dorsal spine (35.5%) and lumbar spine (28.2%). Out of 110 patients, 100 were confirmed as Musculoskeletal tuberculosis which included 92 by HPE and 100 by CBNAAT. The remaining 10 cases which were non tuberculous consisted of 5 cases of metastatic deposits of carcinoma, 3 cases of pyogenic spondylodiscitis, 1 case of primary Giant cell tumour and 1 case of Hemangioma.

Conclusion: Musculoskeletal Tuberculosis is deep seated and paucibacillary condition. Diagnosis is difficult as inadequate sample yield is common. A multifaceted method involving direct smear examination, histopathological examination and CBNAAT is needed to arrive at a definite diagnosis. The gold standard test for diagnosis is culture but it can give false negative results in partially treated cases. Rapid tubercular bacilli detection is made possible by the high sensitivity and specificity of CBNAAT, but it can also produce false-positive results in non-viable bacilli.

Keywords: Musculoskeletal Tuberculosis; Percutaneous Biopsy; Histopathological Examination; CBNAAT

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Citation

Citation: Agarwal VK., et al. “Does Radiology and Pathology Correlate in the Diagnosis of Musculoskeletal Tuberculosis? - A Prospective Study on 110 Patients” Acta Scientific Orthopaedics 6.4 (2023): 02-08.

Copyright

Copyright: © 2023 Agarwal VK., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.