Rajeshwar Nath Srivastava¹*, Zeenat Ara¹, Shah Waliullah¹, Alka Singh¹, Saloni Raj¹ and Lavini Raj²

¹Department of Orthopaedic Surgery, King George’s Medical University, Shahmina Road, Chowk, Lucknow, Uttar Pradesh, India
²Hult International Business School, USA

*Corresponding Author: Rajeshwar Nath Srivastava, Department of Orthopaedic Surgery, King George’s Medical University, Shahmina Road, Chowk, Lucknow, Uttar Pradesh, India.

Received: October 07, 2022; Published: December 15, 2022

Abstract

Spinal cord injury is a life changing threatening neurological condition that completely changes subject’s life. In medical management recent advances has significantly improved diagnosis, stabilization, survival rate and well-being of SCI patients, but there has been very small progression in its treatment, and some such as Stem cell transplantation etc. is very cost effective that is not possible for everyone to afford, so now a days major focus is on nutraceutical supplementation as they are easy to administer and easy to afford, omega 3 fatty acid are important polyunsaturated fatty acids with some roles in normal cellular metabolism, they have Anti-inflammatory and antioxidant properties, and studies have proved its beneficial role in ameliorating inflammation in different diseases and thus plays role in improving neurological outcomes after neuronal injury, studies have shown that in SCI inflammatory events results in activating various inflammatory markers so PUFA 3 helps in suppressing their activity, for healthy adults, the daily recommended level of omega‐3 fatty acid is 300 mg, Leukotriene‐5, thromboxane‐3, and prostaglandin‐3 are derived from essential fatty acids, and are known to be therapeutically important in inflammatory conditions as well as for mental health.
Omega 3 fatty acid helps in modulating multiple pathways that responsible for damage caused after secondary SCI, due to significant health benefits consumption of EPA and DHA is promoted as fatty fishes such as salmon, mullet, and mackerel are the best sources of EPA and DHA so more focus is on aquaculture industries, thus this review tries to cover all possible potential benefits of PUFA. Omega 3 fatty acid helps in modulating multiple pathways that responsible for damage caused after secondary SCI, due to significant health benefits consumption of EPA and DHA is promoted as fatty fishes such as salmon, mullet, and mackerel are the best sources of EPA and DHA so more focus is on aquaculture industries, thus this review tries to cover all possible potential benefits of PUFA.

Keywords: Osteoporosis; Omega 3 Fatty Acid; SCI; EPA; DHA; National Spinal Cord Injury Statistical Centre (NSCISC)

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Citation

Citation: Rajeshwar Nath Srivastava., et al. “Epidemology and Pathophysiology of Spinal Cord Injury and Potential Health Benefits of Omega 3 Fatty Acid”.Acta Scientific Orthopaedics 6.1 (2023): 143-156.

Copyright

Copyright: © 2023 Rajeshwar Nath Srivastava., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.